Blue-emitting perovskite nanocrystals (NCs) are known to exhibit low photoluminescence (PL) quantum yield (QY) compared to green-and red-emitting counterparts, which is due to the presence of localized trap states on the surface. Here, we demonstrate a new method to synthesize high-efficiency blue-emitting perovskite NCs by anion exchange of 0D and 3D perovskite NCs. The remarkable enhancement of the PL QY is caused by surface reconstruction and subsequent suppression of nonradiative recombination centers of 3D perovskite NCs during the anion exchange. Remarkably, these high-efficiency NCs have two appealing applications. First, they can be applied in backlight display, where the GaN light-emitting diode is usually used as the blue emission source. We found that the as-prepared NCs were facile to tune their emission peaks and possessed narrow linewidths. As a downconverter, the NCs realize an ultrapure blue light for backlight display. Second, benefiting from the existence of 0D perovskite, anticounterfeiting inks can also be achieved based on these blue-emitting perovskite NCs. The encoding/reading strategy relies on the conversion of 0D perovskites. These findings provide new opportunities for blue-emitting perovskite NCs and broaden their application.

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This study aimed to improve the surgical removal procedure for nasal vestibular cysts. Twenty-three patients with nasal vestibular cysts underwent surgical removal of the cyst via a transoral sublabial approach and another 30 patients via a modified intranasal endoscopic excision method. The 30 patients were treated with local anesthesia and the roof of the cyst, which was firmly attached to the mucous membrane of the anterior floor of the nasal cavity, was removed transnasally with microdebrider. Bleeding of the opening was stopped by electric coagulation without nasal packing. Among the 30 consecutive patients who underwent the modified surgical procedure, all patients were successfully treated. The mean duration of surgery was 5.7 ± 2.6 min. The mean estimated blood loss was 3.5 ± 2.1 ml. All patients were outpatients. The mean hospital stay was 1 h. The mean total cost was 140. The visual analog scale scores of postoperative pain, pressure and nasal obstruction were 1, 0 and 1, respectively. The incidence rate of postoperative lip swelling or numbness was 0 %. Postoperative endoscopic findings revealed that the cyst was replaced by an air-containing sinus with a persistent opening at the anterolateral nasal floor. There was no recurrence during a mean follow-up of 18 months. The modified intranasal endoscopic excision is a simple, less invasive, low-cost and effective surgical procedure for the treatment of nasal vestibular cysts. It might change the pattern of treatment for nasal vestibular cysts in China.

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Biopotential signals are mainly characterized by low amplitude and thus often distorted by extraneous interferences, such as power line interference in the recording environment and movement artifacts during the acquisition process. With the presence of such large-amplitude interferences, subsequent processing and analysis of the acquired signals becomes quite a challenging task that has been reported by many previous studies. A number of software-based filtering techniques have been proposed, with most of them being able to minimize the interferences but at the expense of distorting the useful components of the target signal. Therefore, this study proposes a hardware-based method that utilizes a shielded drive circuit to eliminate extraneous interferences on biopotential signal recordings, while also preserving all useful components of the target signal. The performance of the proposed method was evaluated by comparing the results with conventional hardware and software filtering methods in three different biopotential signal recording experiments (electrocardiogram (ECG), electro-oculogram (EOG), and electromyography (EMG)) on an ADS1299EEG-FE platform. The results showed that the proposed method could effectively suppress power line interference as well as its harmonic components, and it could also significantly eliminate the influence of unwanted electrode lead jitter interference. Findings from this study suggest that the proposed method may provide potential insight into high quality acquisition of different biopotential signals to greatly ease subsequent processing in various biomedical applications.

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Relapsing polychondritis (RP) is a rare autoimmune disorder of unknown etiology. The disease is characterized by episodic inflammation and destruction of cartilaginous and connective tissue structures, including the ear, eye, nose, larynx, trachea, bronchi, joints, skin, heart valves, and aorta. As the symptoms of RP are diverse and complex, it is easily misdiagnosed. The aim of this paper was to improve the understanding of the clinical features of RP, thereby facilitating its early diagnosis. Fifteen patients with RP were analyzed retrospectively and the relevant literature reviewed. The number of patients presenting with auricular chondritis was 13, while two presented with polyarthritis. Among them, the treatment of 2 RP patients with respiratory tract involvement failed and 1 patient died. Eleven patients with RP (73 %) were initially misdiagnosed. RP involves cartilage and connective tissue. The prognosis for patients with respiratory tract involvement is poor. RP causes episodic and progressive inflammation of cartilage throughout the body and is associated with a variety of clinical manifestations. Early diagnosis of RP depends on a thorough understanding of its clinical features.