Simple innate behavior is often described as hard-wired and largely inflexible. Here, we show that the avoidance of hot temperature, a simple innate behavior, contains unexpected plasticity in Drosophila. First, we demonstrate that hot receptor neurons of the antenna and their molecular heat sensor, Gr28B.d, are essential for flies to produce escape turns away from heat. High-resolution fly tracking combined with a 3D simulation of the thermal environment shows that, in steep thermal gradients, the direction of escape turns is determined by minute temperature differences between the antennae (0.1°–1 °C). In parallel, live calcium imaging confirms that such small stimuli reliably activate both peripheral thermosensory neurons and central circuits. Next, based on our measurements, we evolve a fly/vehicle model with two symmetrical sensors and motors (a “Braitenberg vehicle”) which closely approximates basic fly thermotaxis. Critical differences between real flies and the hard-wired vehicle reveal that fly heat avoidance involves decision-making, relies on rapid learning, and is robust to new conditions, features generally associated with more complex behavior.
The 65 nm Static Random Access Memory (SRAM) based Field Programmable Gate Array (FPGA) was designed and manufactured, which employed tradeoff radiation hardening techniques in Configuration RAMs (CRAMs), Embedded RAMs (EBRAMs) and flip-flops. This radiation hardened circuits include large-spacing interlock CRAM cells, area saving debugging logics, the redundant flip-flops cells, and error mitigated 6-T EBRAMs. Heavy ion irradiation test result indicates that the hardened CRAMs had a high linear energy transfer threshold of upset ∼18 MeV/(mg/cm 2 ) with an extremely low saturation cross-section of 6.5 × 10 −13 cm 2 /bit, and 71% of the upsets were single-bit upsets. The combinational use of triple modular redundancy and check code could decline ∼86.5% upset errors. Creme tools were used to predict the CRAM upset rate, which was merely 8.46 × 10 −15 /bit/day for the worst radiation environment. The effectiveness of radiation tolerance has been verified by the irradiation and prediction results.
It is a crucial question to understand the relationship between public transit and residential rents for the proposal of a sustainable transportation system and efficient allocation of lands during the policy marking process. Little has been discovered in the current literature regarding the impact of the bus system on residential rents. This study investigated walking accessibility to the bus stop based on the average daily on-ridership data of bus stops and street networks in Jinan, China, and analysed the impact on the spatial differentiation of residential rents using the spatial autocorrelation analysis and the geographically weighted regression (GWR) method. Our results suggested that residential rent levels in Jinan had evident spatial dependence and spatial differentiation characteristics, which was signified by a significant high rent, and a high accessibility distribution pattern surrounding both city and sub-city centres. GWR results further showed that walking accessibility to the bus stop could significantly improve residential rents. On the spatial scale, a 1% increase in walking accessibility could result in a premium of up to 0.427% and a 2.984% decline in rental prices. Lastly, we found that walking accessibility to the bus stop significantly affected housing rents incrementally with increasing distance between residences and the city centre. Moreover, walking accessibility to the bus stop showed a marginal ‘first increase and then decrease’ effect on residential rents as the distance to the bus stop increased. The premium effect was the most significant among residences within 500–900 m of a bus stop.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.