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This successful collaboration shows that shared transfusion protocols are feasible and potentially advantageous for hospitals sharing a central blood provider.

As an island nation, Singapore has a small haemophilia population. Through a hybrid health care model which taps on state-funding, medical insurance, the national retirement savings fund and co-payment by patients, our haemophiliacs receive on-demand therapy as standard of care with opportunities for prophylactic treatment if indicated. Recently, we embarked on a comprehensive crosssectional review of our haemophilia A and B populations to determine their current demographic profile and clinical status in order to gauge the performance of our management model and permit forward planning.This study was conducted in 2013 at the three haemophilia treatment centres in Singapore: Singapore General Hospital (SGH), National University Hospital (NUH) and Kandang Kerbau Women's and Children's Hospital (KKH). SGH houses a Comprehensive Haemophilia Treatment Centre (CHTC) and maintains the National Haemophilia Registry. The Registry provided the baseline demographic information on our haemophiliacs while population and health care statistics on Singapore were obtained from the Department of Statistics, Singapore [1]. All haemophiliacs listed in the Registry were invited to participate in this study. Consenting participants answered a set of questionnaires that explores further details of their treatment, complications and socio-economic data. Participants above the age of 4 were also assessed by a site investigator for the status of their joints using the Haemophilia Joint Health Scores (HJHS) version 2.1 [2]. Joint assessments were only conducted in the absence of recent joint bleed or other acute joint symptoms. Data on factor concentrates usage in 2013 were obtained from units dispensing clotting factors at the respective hospitals.Singapore has 195 identified people living with haemophilia A and another 40 people with haemophilia B among a resident population of 3.85 million [2].The prevalence of haemophilia A and B is 10.31 per 100 000 males and 2.11 per 100 000 males respectively. Demographic and clinical characteristics of these individuals are shown in Table 1. Inhibitors developed in 17.9% of our haemophilia A population [8.2% persistent, 5.6% high responders]. Only one haemophilia B individual had inhibitors. Immune tolerance induction (ITI) therapy was successfully given to two haemophilia A adults with inhibitors using a dose regimen of 100 IU kg À1 day À1 without additional immunosuppressive therapy. One third (30.2%) of our haemophilia A and 20% of our haemophilia B population had no family history of haemophilia.Ninety-two individuals with haemophilia A and 16 with haemophilia B from the ages of 1-79 consented to contributing further socio-economic and clinical data. They represented 19.4%, 56.2% and 67.2% of the mild, moderate and severe haemophilia A population respectively and 40% of the haemophilia B population. The bleeding profile and bleeding-related complications of participating individuals as well as their current mode of treatment, type of product used and access to home treatment is shown in Table...

CRRT using the HF20 membrane is safe and hemodynamically well tolerated in high-risk, unstable low-body-weight infants with cardiac dysfunction on multiple inotropes.

We present a novel, low-cost, easily constructed, realistic BMAT simulator for training novice doctors to perform BMAT.

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