Magnetite nanoparticles were obtained by liquid phase precipitation method in which the pH
value of [FeCl2⋅4H2O], [FeCl3⋅6H2O] and [NaOH] solution were controlled. Then the magnetite
nanoparticle were scattered in water solution and put in [Na2SiO3] and [HCl], the resultant of reaction
SiO2 can be coated on magnetite nanoparticles surface. The morphology and magnetite properties of the
coated nanoparticles were evaluated by XRD, TEM, FTIR and VSM. The SiO2 thin film with nanometer
size was coated on surface of nanoparticle, so that the magnetic value is decreased with the coating
thickness increasing.
In this study, the composite magnetic nanoparticles of coated SiO nano film with about 8 nm size and high saturation magnetization value, were synthesized by liquid phase precipitation method. The magnetic nanoparticles can be dispersed in various liquid media, widely known as magnetic fluids or ferrofluids with both magnetic and liquid properties. The materials been collected great interests and more and more attentions to focus into Drug Delivery System (DDS) as a new technology in this paper. We use the composite nanoparticles to disperse H2O and inject the solutions into rat's in-vivo organs. And, in the experiments by using a strong photon beam of SPring-8 Synchrotron Radiation facility, the distribution stat and the effects of magnetic field as well as drug delivery behaviour of nanoparticles in the rat' kidney are verified by the in-vivo observations.
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