This roundtable was conducted by the eight founding members of Decolonising Design Group in October 2017, using an online messaging platform. Each member approached design and decoloniality from different yet interrelating viewpoints, by threading their individual arguments with the preceding ones. The piece thus offers and travels through a variety of subject matter including politics of design,

In the last years, science courses in higher education (HE) have been facing some problems, namely the lack of students' motivation, the number of students' failures and drop outs, particular in physics courses. The most probable reason, which has been mentioned in current science education research in HE, is that the level of interaction between teachers and learners in formal instructional settings is very low. In this paper, we describe changes that were introduced in lectures towards the promotion of active learning and analyse its effects in the classroom environment. The introduction of conceptual questions and peer instruction seems to motivate students in the class and help them engage in the learning process. These strategies have been used in the first year of an introductory physics course for engineering students in two different Portuguese HE institutions. The data were collected through questionnaires and student interviews.

Alveolar soft-part sarcoma (ASPS) is a rare, clinically, morphologically, ultrastructurally, and cytogenetically distinctive malignant mesenchymal tumor that most classically occurs in the extremities of adolescents and young adults, but has also been described in a number of unusual sites. The molecular signature of ASPS is a specific der(17)t(X;17)(p11.2;q25) translocation, which results in the fusion of TFE3 transcription factor gene (from Xp11) with ASPL at 17q25. The ASPL-TFE3 fusion protein encoded by the fusion transcript can be detected immunohistochemically with commercially available antibodies to the carboxy terminus of TFE3. Herein, we report a unique case of ASPS presenting in the bladder with subsequent urethral recurrence in a 25-year-old woman. We emphasize the differential diagnoses engendered by ASPS including common, not-so-common, and rare tumors involving the urinary bladder that have a nested architecture, and both clear and eosinophilic cytoplasm, and demonstrate the utility of a broad immunohistochemistry panel including TFE3 for diagnosis.

A Surdez Infantil é considerada actualmente um verdadeiro problema de Saúde Pública devido não só à sua elevada prevalência, mas sobretudo às múltiplas conseqüências que acarreta sob os mais variados prismas. Trata-se de um tema em constante evolução, sendo necessárias freqüentes actualizações por forma a acompanhar os avanços da técnica e do conhecimento. Este trabalho visa abordar de uma forma global mas sucinta o problema Surdez Infantil, dando particular ênfase aos Modelos de Rastreio e aos Métodos utilizados com esse fim. Chi ldhood Hearing Impairment is nowadays considered as a Health Care matter due to its high prevalence and to its multiple consequences. As a developing subject, frequent updates are justified to keep up with the evolution of techniques and knowledge. This paper aims to discuss the matter from a global point of view, paying particular attention to the Screening Models and Instruments available. Rev Bras Otorrinolaringol. V.68, n.3, 417-23, maio/jun. 2002 Palavras-chave: surdez infantil, otoemissões acústicas, potenciais evocados, rastreio. Pedro REVIEW ARTICLE ARTIGO DE REVISÃO

• Gadofosveset-enhanced MRI shows high performance for nodal (re)staging in rectal cancer. • Gadofosveset MRI may facilitate better selection of patients for personalised treatment. • Results can be reproduced by non-expert readers. • Experience of 50-60 cases is required to achieve required expertise level. • Main pitfalls are nodes located between vessels and nodes containing micrometastases.

Our study demonstrates a significant myocardial fibrosis induced by low frequency noise in rats. Our results reinforce the need for further experimental and clinical investigations concerning the effects of low frequency noise on the heart.

There are perivascular structural modifications in arterial coronary vessels. Our results show a significant development of periarterial fibrosis induced by industrial noise in the rat heart.

Background: Chronic exposure to industrial noise is known to affect biological systems, namely, by inducing fibrosis in the absence of inflammatory cells. In rat hearts exposed to this environmental hazard, we have previously found myocardial and perivascular fibrosis. The acoustic spectrum of industrial environments is particularly rich in high-intensity infrasound (b20 Hz), whose effects on the heart are unknown. We evaluated the morphological changes induced by IFS in rat coronaries in the presence and absence of dexamethasone. Methods: Adult Wistar rats were divided into three groups: group A (GA)-IFS (b20 Hz, 120 dB)-exposed rats for 28 days treated with dexamethasone; group B (GB)-IFS-exposed rats; group C (GC)-age-matched controls. The midventricle was prepared for observation with an optical microscope using 100× magnification. Thirty-one arterial vessels were selected (GA 8, GB 10, GC 13). The vessel caliber, thickness of the wall, and perivascular dimensions were quantified using image J software. Mann-Whitney and Kruskal-Wallis tests were used to compare the groups for lumen-to-vessel wall (L/W) and vessel wall-to-perivascular tissue (W/P) ratios. Results: IFS-exposed rats exhibited a prominent perivascular tissue. The median L/W and median W/P ratios were 0.54 and 0.48, 0.66 and 0.49, and 0.71 and 0.68, respectively, in GA, GB, and GC. The W/P ratio was significantly higher in GC compared with IFS-exposed animals (P=.001). The difference was significant between GC and GB (P=.008) but not between GC and GA. Conclusion: IFS induces coronary perivascular fibrosis that differs under treatment with corticosteroid.