As interest in using carbon nanotubes for developing biologically compatible systems continues to grow, biological inspiration is stimulating new directions for in vivo approaches. The ability to integrate nanotechnology-based systems in the body will provide greater successes if the implanted material is made to mimic elements of the biological milieu especially through tuning physical and chemical characteristics. Here, we demonstrate the highly successful capacity for in vivo implantation of a new carbon nanotube-based composite that is, itself, integrated with a hydroxyapatite-polymethyl methacrylate to create a nanocomposite. The success of this approach is grounded in finely tailoring the physical and chemical properties of this composite for the critical demands of biological integration. This is accomplished through controlling the surface modification scheme, which affects the interactions between carbon nanotubes and the hydroxyapatite-polymethyl methacrylate. Furthermore, we carefully examine cellular response with respect to adhesion and proliferation to examine in vitro compatibility capacity. Our results indicate that this new composite accelerates cell maturation through providing a mechanically competent bone matrix; this likely facilitates osteointegration in vivo. We believe that these results will have applications in a diversity of areas including carbon nanotube, regeneration, chemistry, and engineering research.
The new IEEE 802.21 standard specifies link layer intelligence and other related network information to upper layers in order to optimize handovers between networks of different types, such as WiMAX, Wi-Fi, and 3GPP. This paper makes a short description of 802.21 standard, how it is implemented in ns-2, and the signaling used in a handover between WiMAX and Wi-Fi. The paper also proposes a novel and very simple approach to determine the expected number of handovers in an ns-2 simulation and also evaluates the reliability and scalability of ns-2 when simulating 802.21 scenarios with multiple nodes.
This paper describes the implementation and the technical specifications of a geolocation database assisted by a spectrum-monitoring outdoor network. The geolocation database is populated according to Electronic Communications Committee (ECC) report 186 methodology. The application programming interface (API) between the sensor network and the geolocation database implements an effective and secure connection to successfully gather sensing data and sends it to the geolocation database for post-processing. On the other hand, the testbed allows authorized TV white space devices to gain access to the services of the geolocation database, according to a draft implementation of Internet Engineering Task Force (IETF) Protocol to Access White Space (PAWS) Two experimental methodologies are available with the testbed: one focused on coexistence studies with commercial wireless microphones, when the testbed is used for sensing only, and another for demonstration purposes, when the testbed is also used to emulate wireless microphone signals. Overall, this hybrid approach is a promising solution for the effective use of TV white spaces and for the coexistence with digital TV broadcast signals, or dynamic incumbent systems, such as unregistered wireless microphones.
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