Aim The purpose of this review is to present the potential for the incorporation of ozone therapy into the practice of dentistry. Background Ozone gas has a high oxidation potential and is 1.5 times greater than chloride when used as an antimicrobial agent against bacteria, viruses, fungi, and protozoa. It also has the capacity to stimulate blood circulation and the immune response. Such features justify the current interest in its application in medicine and dentistry and have been indicated for the treatment of 260 different pathologies. It can be used for the treatment of alveolitis as a replacement for antibiotic therapy, as a mouthwash for reducing the oral microflora, as well as the adherence of microorganisms to tooth surfaces. Ozone has been shown to stimulate remineralization of recent caries-affected teeth after a period of about six to eight weeks. Conclusion The future of ozone therapy must focus on the establishment of safe and well-defined parameters in accordance with randomized, controlled trials to determine the precise indications and guidelines in order to treat various medical and dental pathologies. Scientific support, as suggested by demonstrated studies, for ozone therapy presents a potential for an atraumatic, biologically-based treatment for conditions encountered in dental practice. Citation Nogales CG, Ferrari PA, Kantorovich EO, Lage-Marques JL. Ozone Therapy in Medicine and Dentistry. J Contemp Dent Pract 2008 May; (9)4:075-084.

Enterococci, enteric bacteria and yeasts were present in primary endodontic infections. Enterococci, particularly Enterococcus faecalis and E. faecium were resistant to removal by root canal preparation followed by intracanal dressing.

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Irrigation with 5.25% NaOCl and 1% NaOCl alternated with 15% citric acid reduced microorganisms in infected root canals significantly more than saline and 1% NaOCl.

Calcium hydroxide used as intracanal medication for 14 days had a positive influence on the bond strength of AH to root dentin whereas the effect on EP was insignificant. Regardless of the intracanal medication used, AH showed considerably higher bond strength values compared with EP sealer.