Many unsolved practical issues, from technical and scientific to ethical, legal and economic topics, are slowing down the translation of Personalized Medicine principles into medical practice. The Italian Society of Personalized Medicine exposes here its point of view, based on the real-world practice of precision medicine carried-out in Italian healthcare structures.
ObjectiveSide effects of antiretroviral therapy (ART) can have a negative impact on health-related quality of life threatening long-term retention in HIV care and adherence to ART. The aim of the French community-based survey EVE was to document personal experiences with side effects, the related physician-patient communication, and solutions found to deal with them.DesignCross-sectional study of women between September 2013 to September 2014MethodsAn anonymous online questionnaire included the HIV Symptom Distress Module, which explores 20 symptoms.ResultsIn all, 301 women on ART participated in the study (median age: 49 years; median duration of ART: 14 years). They reported having experienced a median of 12 symptoms (Q1-Q3: 9–15) during the previous 12 months. Overall, 56% of them reported having found at least a partial solution to dealing with their symptoms. Women reporting financial difficulties were twice less likely to have found solutions to coping with their side effects (AOR: 0.5; 95% CI: 0.3–0.8). Feeling supported by the health-care provider (AOR: 2.1; 95% CI: 1.1–3.9) and being in contact with HIV/AIDS organisations (AOR: 1.9; 95% CI: 1.2–3.2) were positively associated with coping. Seventeen percent reported having modified their ART regimen to improve tolerance, with only 2 in 3 informing their physician afterwards. Reporting financial difficulties and living with more bothersome symptoms increased the risk of ART regimen modification without health-care provider consultation.ConclusionThe EVE study has called attention to the large number of side effects experienced by WLWHIV, only half of whom have found self-care strategies to manage their symptoms. Modification of ART regimen by the women themselves was not uncommon.
No abstract
The treatment protocol form defines all health care and treatments that are free of charge for patients living with a long-term disease in France. It is designed to facilitate the medical care of these patients. The way in which it is written impact on access and adequacy of health care. AIDES, a French HIV/AIDS/Hepatitis association, reported disparities and shortcomings in the use of this protocol. A survey was conducted among people attending this association in order to objectively demonstrate field observations. This article presents the results of this investigation designed to determine the level of knowledge of the people living with HIV and/or hepatitis in contact with the association regarding the use of this protocol. 224 people completed the questionnaire. The results confirm field observations: the appropriation of the treatment protocol by patients who participated in this survey remains limited, even within a study population in contact with a patient association. These findings raise the question of the effectiveness of the communication between health care practitioners/caregivers and patients concerning the use of this tool. More widely, the protocol drafting process needs to be reviewed: what are the respective places and roles for health stakeholders? What form of coordination between the patient, the general practitioner and the Health Insurance is required to establish an appropriate and appropriable treatment protocol?
No abstract
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.