A decrease in delay of cleavage, when irradiated sperm fom Arbacia punctulata were allowed to "recover" inside eggs, occurred when cell division was interrupted by the removal of oxygen soon after fertilization. The recovery mechanisms in irradiated eggs of this species before and after fertilization have been compared and appear to differ.
Bone studies have shown that thyroid hormones may reduce the whole-body retention (WBR) of bone-bound 85Sr in young growing CF, albino mice. Treatment with thyroxin (5, 10, 20 ,ug/day) and triiodothyronine (5, 10 pg/day) at all dose levels lowered the WBR of =Sr 10-12 per cent, and the effect was maximal after 3-4 weeks. The effects of tetraiodothyroacetic acid and triiodothyroacetic acid were dose dependent; 10-pg levels of each hormone were ineffective, but 30 pg lowered the WBR 5 per cent after 4-5 weeks. While the process by which the thyroid hormones effect the reduction of bone-bound radiostrontium is not fully understood, possible mechanisms have been discussed.
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