Celery (Apium graveolens L.) has been known as traditional medicine. Apigenin is one of active component in Celery leaf that has fungicidal activity, so celery leaf's extortion suspected has fungicidal activity to Candida albicans. Apigenin can solved in water. The aim of this research was to know antifungal activity of celery leaf's extortion againsts Candida albicans in vitro. This is a laboratory experimental research by using completely randomized design and disc diffusion method. Celery leaf's extortion was divided into 3 concentrations, there were 25%, 50% and 100%. Ketoconazole 2% was used as positive control and aquadest as negative control. The result of this research was based on analysis of variance, there was significant difference between minimal 2 treatment (p=0.000) and confirmed with Post Hoc test, there were significant difference in all treatments. As the conclusion, celery leaf's extortion had antifungal activity againsts Candida albicans in vitro with the best concentration 50% but smaller than ketoconazole 2%. Keywords: antifungal activity, celery (Apium graveolens L.), Candida albicansPengobatan menggunakan tumbuh-tumbuhan (pengobatan tradisional) sudah dikenal jauh sebelum pelayanan kesehatan dengan obat modern digunakan oleh masyarakat luas. Para ilmuwan saat ini, banyak melakukan penelitian kembali terhadap tumbuhan obat. Obat sintetik yang ada saat ini, beberapa diantaranya ditemukan efek samping dan komplikasi terhadap kesehatan manusia.
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