This study demonstrated that the addition of acarbose to patients with type 2 diabetes who are inadequately controlled with insulin and diet is safe and generally well tolerated and that it significantly lowers HbA1c and postprandial glucose levels.
The present work describes a laboratory assay for individuals predisposed to cancer within NF pedigrees. The assay is based on the association between the increased sensitivity of human skin fibroblasts to transformation by the Kirsten murine sarcoma virus and predisposition to cancer in clinically affected patients and in otherwise apparently healthy individuals within NF pedigrees. The more sensitive the cells are to transformation by KiMSV, the greater the probability that a person from whom such cells have been derived will develop cancer. The results show a strong correlation with the NF trait. Together with the clinical data this laboratory assay could, therefore, be used to ascertain the NF genotype.
Research on external spinal compression has consisted mainly of laboratory-based evaluations of specific exercise interventions on spinal compression in athletes and industrial employees. The purpose of this pilot study was to test the reliability of a seated stadiometry device for measuring external spinal compression in a sample of nurses and non-nurses. This research will be used to study nurses in future studies. Twenty-three subjects were marked externally at the C 7 spinal process. Two investigators collected measures of seated spinal length. Six measurements were taken within a five-minute period on the morning of day one, repeated four hours later, and one week later. Comparisons were made using ANOVA between (1) three sets of repeated measures;(2) inhalation and exhalation; (3) morning and afternoon sessions; and (4) weeks one to two. A statistically significant difference was found in mean measures of displacement (−2.29 mm to −4.07 mm) between morning and afternoon but not between inhalation and exhalation or in successive weeks. Inter-rater reliability between two investigators was excellent. The stadiometer proved highly reliable. It will be used to investigate the relationship between spinal compression and back pain in nurses in the workplace.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.