Self-ordered particle trains in inertial microchannel flows. (2017) Microfluidics and Nanofluidics, 21 (10).

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Finite-size neutrally buoyant particles in a channel flow are known to accumulate at specific equilibrium positions or spots in the channel cross-section if the flow inertia is finite at the particle scale. Experiments in different conduit geometries have shown that while reaching equilibrium locations, particles tend also to align regularly in the streamwise direction. In this paper, the Force Coupling Method was used to numerically investigate the inertia-induced particle alignment, using square channel geometry. The method was first shown to be suitable to capture the quasisteady lift force that leads to particle cross-streamline migration in channel flow. Then the particle alignment in the flow direction was investigated by calculating the particle relative trajectories as a function of flow inertia and of the ratio between the particle size and channel hydraulic diameter. The flow streamlines were examined around the freely rotating particles at equilibrium, revealing stable small-scale vortices between aligned particles. The streamwise inter-particle spacing between aligned particles at equilibrium was calculated and compared to available experimental data in square channel flow (Gao et al. Microfluidics and Nanofluidics 21, 154 (2017)). The new result highlighted by our numerical simulations is that the inter-particle spacing is unconditionally stable only for a limited number of aligned particles in a single train, the threshold number being dependent on the confinement (particle-to-channel size ratio) and on the Reynolds number. For instance, when the particle Reynolds number is ≈ 1 and the particle-to-channel height size ratio is ≈ 0.1, the maximum number of stable aligned particles per train is equal to 3. This agrees with statistics realized on the experiments of (Gao et al. Microfluidics and Nanofluidics 21, 154 (2017)). It is argued that when several particles are hydrodynamically connected moving as a unique structure (the train) with a steady streamwise velocity, large-scale hydrodynamic perturbations induced at the train scale prohibit small-scale vortex connection between the leading and second particles, forcing the leading particle to leave the train. arXiv:1810.08670v1 [physics.flu-dyn]

Understanding the behavior of a single particle flowing in a microchannel is a necessary step in designing and optimizing efficient microfluidic devices for the separation, concentration, counting, detecting, sorting, or mixing of particles in suspension. Although the inertial migration of spherical particles has been deeply investigated in the last two decades, most of the targeted applications involve shaped particles whose behavior in microflows is still far from being completely understood. While traveling in a channel, a particle both rotates and translates: it translates in the streamwise direction driven by the fluid flow but also in the cross-section perpendicular to the streamwise direction due to inertial effects. In addition, particles’ rotation and translation motions are coupled. Most of the existing works investigating the transport of particles in microchannels decouple their rotational and lateral migration behaviors: particle rotation is mainly studied in simple shear flows, whereas lateral migration is neglected, and studies on lateral migration mostly focus on spherical particles whose rotational behavior is simple. The aim of this review is to provide a summary of the different works existing in the literature on the inertial migration and the rotational behavior of non-spherical particles with a focus and discussion on the remaining scientific challenges in this field.

The inertial migration of particles in microchannel flows has been deeply investigated in the last two decades. In spite of numerous reports on the inertial focusing patterns in a square channel, the particle inertial focusing and longitudinal ordering processes remain unclear at high Reynolds numbers (>200) in square microchannels smaller than 100 µm in width. Thus, in this work, in situ visualization of particles flowing in square micro-channels at Reynolds numbers Re ranging from 5 to 280 has been conducted and their migration behaviors have been analyzed. The obtained results confirm that new equilibrium positions appear above a critical Re depending on the particle to channel size ratio and the particle volume fraction. It is also shown that, for a given channel length, an optimal Reynolds number can be identified, for which the ratio of particles located on equilibrium positions is maximal. Moreover, the longitudinal ordering process, i.e., the formation of trains of particles on equilibrium positions and the characterization of their length, has also been analyzed for the different flow conditions investigated in this study.

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