Enantio- and regioselective: The intramolecular enantioselective aminofluorination of unactivated olefins was achieved by using a chiral iodo(III) difluoride salt. A highly regioselective aminofluorination of styrenes to access 2-fluoro-2-phenylethanamines was also developed.

Enantio‐ und regioselektiv gelingt die intramolekulare enantioselektive Aminofluorierung nichtaktivierter Olefine mit einem chiralen Iod(III)‐difluorid‐Salz. Überdies wurde eine hoch regioselektive Aminofluorierung von Styrolen als Zugang zu 2‐Fluor‐2‐phenylethanaminen entwickelt.

No abstract

Regio-and Enantioselective Aminofluorination of Alkenes. -The intramolecular metal-free aminofluorination of unactivated alkenes works with aryl iodonium difluorides as the reagent. A lactate derivative such as BLI is used to induce chirality. An achiral version concerning the intermolecular process is also developed. -(KONG, W.; FEIGE, P.; DE HARO, T.; NEVADO*, C.; Angew. Chem., Int. Ed. 52 (2013) 9, 2469-2473, http://dx.doi.org/10.1002/anie.201208471 ; Org.-Chem. Inst., Univ. Zuerich, CH-8057 Zuerich, Switz.; Eng.) -Mais 29-155