Steven‐Johnson syndrome (SJS) is a severe cutaneous adverse drug reaction. Its occurrence due to vaccines is scant.
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We report a case of SJS caused by COVID‐19 vaccine in an adult.
A 60‐year‐old male presented with complaints of fever, oral ulceration and skin rash three days after the first dose of COVID‐19 vaccine, for which he visited a local physician and was prescribed paracetamol and levocetrizine, inspite of which the symptoms were not controlled and gradually the rashes became generalised in distribution.
BackgroundCutaneous vascular malformations and tumors comprise a vast group of conditions with variable clinical presentations. It is imperative to differentiate them from nonvascular lesions and from each other as their management and prognosis differ significantly. There is only sparse literature on dermoscopic features of various vascular malformations and tumors, especially from India.
A 30-year-old male had a single asymptomatic, slow-growing lesion on the tip of the tongue for six months. He denied any prior history of trauma or surgical procedure at the site. His medical history was unremarkable. Cutaneous examination showed a solitary well-demarcated flesh-coloured, dome-shaped, smooth, firm, non-tender papule of size 4 mm × 4 mm on the tip of the tongue [Figure 1]. The dermoscopic examination under polarised mode (Heine Delta 20T, ×10 magnification) revealed a central white homogeneous area and a peripheral corona of hairpin vessels [Figure 2]. The differential diagnoses of traumatic fibroma, granular cell tumour, Heck's disease, and angiofibroma were considered. Pathological examination showed a moderately acanthotic epidermis, a collagenous stroma with numerous dispersed dilated blood vessels and scattered fibroblasts. In addition, inflammatory cell infiltration was absent. The diagnosis of traumatic fibroma was made, and the patient was counselled about the benign nature. The white homogeneous area corresponds to the acanthotic epidermis along with dermal collagen and the hairpin vessels to the dilated papillary dermal blood vessels.
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