Silver nanoparticles size makes wide range of new applications in various fields of industry. Synthesis of noble metal nanoparticles for applications such as catalysis, electronics, optics, environmental and biotechnology is an area of constant interest. Two main methods for Silver nanoparticles are the physical and chemical methods. The problem with these methods is absorption of toxic substances onto them. Green synthesis approaches overcome this limitation. Silver nanoparticles size makes wide range of new applications in various fields of industry. This article summarizes exclusively scalable techniques and focuses on strengths, respectively, limitations with respect to the biomedical applicability and regulatory requirements concerning silver nanoparticles.

Objective: The aim of this study is to modify the World Health Organization (WHO) Surgical Safety Checklist in order to be compatible to a hospital in Iran and measure effect of implementing this checklist on postoperative complications. Methods: In a cross-sectional study the views of surgeons and anesthesiologists of the main teaching hospital in Tabriz -Imam Reza Hospital-were taken by a form attached to the main checklist. The participants in this study asked to write their opinions on each item of checklist based on the environment of the hospital. Then, we performed before-after study to determine effect of a modified checklist implementing on postoperative complications. Results: Surgeons and anesthesiologists had consensus on 15 of 19 items of checklist to remain the same and just 4 items recommended to be changed. In pre intervention period of study, 100 patients (51 males and 49 females) were enrolled with the mean age of 48.5±13.5years. The number of patients in the post intervention period was the same, but 49 males and 51 females, the mean age was 47.5 ±14.6 years. The incidence of any complications in pre intervention period was 30%, but this rate in post intervention period was 12% and the difference between 2 periods of study was statistically significant (p=0.002). Conclusion: World Health Organization Surgical Safety Checklist is betterto modify based on the local needs and facilities in each hospital. After implementing of a modified surgical safety checklist, complications decreased by 58%.

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