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Background: To compare the efficacy of oxytocin, methylergometrine and misoprostol in active management of third stage of labour (AMTSL).Methods: A clinical study was conducted on 330 low risk pregnant women with a healthy singleton pregnancy and spontaneous onset of labour at term; allocated into three groups where active management of third stage of labour was done with either Oxytocin 10 IU intramuscular, or Methylergometrine 0.2 mg intramuscular, or tab Misoprostol 600µg sublingual on 110 women each group. Primary parameter was blood loss during labour. Secondary parameters were the duration of third stage of labour and changes in haemoglobin level.Results: Blood loss during labour in Oxytocin group was 145.86±11.53 ml, which was significantly less than that in Methylergometrine (164.02±9.36 ml) and Misoprostol groups (183.18±9.70 ml), but no patient in any of the groups had blood loss more than 200ml. Duration of third stage of labour was significantly less in Oxytocin group (5.13±1.91 mins) than in. Methylergometrine (6.16±1.85 mins), and Misoprostol groups (6.47±1.51 mins). No patient had prolonged third stage in any of the groups. There was no significant change in pre-and post-delivery haemoglobin levels in all the groups.Conclusions: Though injectable uterotonics are effective for active management of third stage of labour (AMTSL), misoprostol can also be effectively used, especially in settings where there is no adequate trained personnel and drug storage facility.

BACKGROUND:Dengue is an RNA virus of the family Flaviviridae transmitted by Aedes mosquitoes particularly Aedes aegypti. It is widely distributed throughout the tropics and subtropics and in a small proportion of cases the virus leads to life threatening complications dengue hemorrhagic fever and dengue shock syndrome. OBJECTIVES: To study the early diagnosis of Dengue on day 1 as there is no vaccine or specific antiviral treatment available. METHODS: A prospective study of 104 patients was done based on clinical criteria of Dengue. RESULTS: Out of 104 serum samples 46 (44%) were positive by NSI Ag MICROELISA, 37 (35%) by NSI antigen IMMUNO CHROMATOGRAPHY. 3 (2%) samples are positive by IgM IMMUNO CHROMATOGRAPHY and only one sample was positive for IgG IMMUNOCHROMATOGRAPHY. CONCLUSION: The present study has established the significance of NSI Ag MICROELISA with NSI antigen IMMUNO CHROMATOGRAPHY in increasing the diagnostic efficiency in the day 1 diagnosis of Dengue fever.

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Clostridium tetani is the causative agent of Tetanus. The aim was to detect the presence of Clostridium tetani in a case of suspected Tetanus in a 40 year old male who had history of handling a a thorn injury in the agricultural field 15 days ago. The patient presented with spasm of all the limb muscles and Lockjaw of 2 days duration together with history of convulsions for the last 3 days. Bits of tissue were collected from the necrotic depth of the wound abscess and were analyzed. Clostridium tetani was isolated. A diagnosis of Tetanus was made and the concerned authority was immediately notified. The patient was successfully treated with complete recovery. An early diagnosis of TETANUS is significant because it can help the clinician in early management and prevention of development of terminal respiratory failure and death.

Background: India is going to be highest populous country within less than a decade. To stabilize population growth as well as to reduce maternal mortality and morbidity resulting from unwanted pregnancy, greater utilization of the spacing methods is essential. In spite of several decades of effort the popularity of Cu-T among the Indian woman is not high. Aim of the study was to find out the profile of the Cu-T acceptor after medical termination of pregnancy (MTP).Methods: It was a retrospective study. Socio-demographic data of the woman accepting Cu-IUCD after MTP was collected from family planning operation theatre record book.Results: The majority of the participants were from rural area. The mean age of the acceptor was 27.28±4.78. The maximum number of woman was para two 74 (44.3%). The number of woman with LCB 2 years or less than 2 years was 96 (57.5%) and that of woman with LCB more than two years was 71 (42.5%).Conclusions: A significant number of woman use Cu-T after a long gap of two years after last child birth. Woman found to be inclined to use Cu-T after having at least one male child.