Introduction and aims
The demographic and clinical profile and dynamics of real-time polymerase chain reaction (RT-PCR) in coronavirus disease 2019 (COVID-19) patients are not well understood. The study aimed to analyze the demographic, clinical, and RT-PCR profiles of COVID-19 patients.
Methodology
The study was a retrospective, observational study conducted at a COVID-19 care facility, and the study period was from April 2020 to March 2021. Patients with laboratory-confirmed COVID-19 by real-time polymerase chain reaction (RT-PCR) were enrolled in the study. Patients with incomplete details or with only single PCR tests were excluded. Demographic and clinical details and the results of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RT-PCR collected at different time points were retrieved from the records. The statistical software Minitab version 17.1.0 package (Minitab, LLC, State College, PA, USA) and Rstudio version 1.3.959 (Rstudio, Boston, MA, USA) were used for the statistical analysis.
Results
The mean duration from symptom onset to the last positive RT-PCR was 14.2 ± 4.2 days. The proportions of positive RT-PCR tests were 100%, 40.6%, 7.5%, and 0% at the end of the first, second, third, and fourth weeks of illness. The median duration of days to first negative RT-PCR in the asymptomatic patients was 8 ± 4 days, and 88.2% of asymptomatic patients were RT-PCR-negative within 14 days. A total of 16 symptomatic patients had prolonged positive test results even after three weeks of symptom onset. Older patients were associated with prolonged RT-PCR positivity.
Conclusion
This study revealed that the average period of RT-PCR positivity from the onset of symptoms is >2 weeks in symptomatic COVID-19 patients. Prolonged observation in the elderly population and repeat RT-PCR before discharge or discontinuation of quarantine is required.
Background With advancing age s various methods have been practiced to dissect the palatine tonsils. The methods of tonsillectomy have been broadly grouped as hot and cold tonsillectomy. To analyze Aim & Objective the use and effectiveness of the electrodissection method in comparison to the cold dissection with ligation method in terms of the intraoperative haemorrhage and the duration the procedure of Tonsillectomy. This hospital based obse Methods rvational study was conducted at a tertiary care hospital situated in Diphu, Assam, from March 2021 to March 2023, after obtaining the ethical committee clearance. Total 40 patients were selected to be included in this study. Tonsillectomy was done by the electrodissection method and the cold dissection method in either side of the same patient and the results obtained were compared. The mean blood loss Results during the electrodissection tonsillectomy (for one side) was 11.60 ± 4.24 mL, whereas, in cold tonsillectomy (for one side) the mean intra operative blood loss was 42.73 ± 6.42 mL . The mean duration for the electrodissection tonsillectomy was 8.68 ± 2.09 minutes, whereas the mean time for performing the cold dissection method was 25.65 ± 4.15 minutes. Both of these results are highly signicant with p- value < 0.001. Elec Conclusion trodissection tonsillectomy is reliably a faster and a safer method and it may be of greater use in high risk patients.
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