Digital mammography may be more effective than screen-film mammography in contemporary screening practice in mobile units. The data indicate that digital mammography depicts more tumors than does screen-film mammography, especially lesions seen as microcalcifications. The potential association with improved outcome warrants further study.
We assessed the correlation between quantitative results of immunological faecal occult blood testing (I-FOBT) and colonic lesions (191 colorectal cancers, 890 adenomas) detected at colonoscopy in 2597 FOBT þ (cutoff 100 ng ml À1 Hb) subjects. At univariate analysis, a higher average faecal Hb content was significantly associated with male gender (P ¼ 0.003), age (P ¼ 0.02), and colonoscopy findings (P ¼ 0.000). Among adenomas, higher faecal Hb content was significantly associated with size (P ¼ 0.0000), presence of severe dysplasia (P ¼ 0.0001), presence of villous component (P ¼ 0.0002), and location in the left colon (P ¼ 0.003). At multivariate analysis adjusting for potential confounders, age (P ¼ 0.03), size (P ¼ 0.0000), and location in the left colon (P ¼ 0.0005) were confirmed as having an independent association with higher faecal Hb content. Immunological FOBT is confirmed to be a specific screening test to detect cancer and adenoma, with a low positivity rate (3.7%) and a high positive predictive value (41.5%). Faecal Hb content is significantly higher for those lesions (cancer and high-risk adenomas) screening is aimed at detecting. British Journal of Cancer (2007)
Reduced preparation increases participation in CTC. Lower attendance and higher DR of CTC as compared with FIT are key factors for the optimization of its role in population screening of CRC.
The quality of colonoscopy was affected by patient-related, endoscopist-related and centre-related characteristics. Policies addressing organisational issues should improve the quality of colonoscopy in our programme and similar programmes.
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