An immunoassay is mostly employed
for the direct detection of food
contaminants, and a molecular assay for targeting nucleic acids employs
amplification techniques for distinguishing genes. The integration
of an immunoassay with nucleic acid amplification techniques inherits
the direct and rapid performance of an immunoassay and the ultrasensitive
merit of a molecular assay. Enthusiastic attention has been attracted
in recent years on the utilization of isothermal amplification techniques
in an immunoassay, as well as the employment of a lateral flow immunoassay
in a molecular assay. Thus, this Review discussed these kinds of approaches
from two categories: immuno-nucleic acid amplification (I-NAA) and
nucleic acid amplification-immunoassay (NAA-I). The advantages, drawbacks,
and future developments were discussed for a comprehensive understanding.
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