All the absorbed doses were comparable with those known for most of the 99mTc studies. 99mTc-HYNIC-BN shows high tumor uptake in breasts with malignant tumors so it is a promising imaging radiopharmaceutical to target site-specific early breast cancer. The results obtained warrant a further clinical study to determine specificity/sensibility of 99mTc-HYNIC-BN.

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Conservative surgery is an effective surgical-alternative to chemo-radiotherapy in patients with locally advanced laryngeal cancer, providing oncological control, acceptable complications and minimal sequels. Although most patients have aspiration, this does not affect functional status.

Introduction: Supracricoid subtotal laryngectomy associated with cricohyoidoepiglottopexy is the most efficient conservative surgical technique to preserve laryngeal functions in patients with locally advanced carcinoma of the larynx. The most feared complication of this intervention is aspiration at the moment of swallowing and secondary pneumonia; there are several ways to evaluate aspiration and its degree. We present a novel form to identify even small amounts of tracheobronchial aspiration. Method: Patients undergoing subtotal laryngectomy and cricohyoidoepiglottopexy due to laryngeal cancer were included; all of them were postoperatively assessed with radioactive-swallow. Based on the symptoms and the scintigraphy result, prolonging the feeding time by nasogastric tube was decided. Results: Thirty-seven patients were included; 4 of them had received radiotherapy; aspiration rate was 29.7 %; 50 % of patients who had received radiation had aspiration; 18 % of subjects with tracheobronchial aspiration required prolongation of feeding time by nasogastric tube, none required total laryngectomy for aspiration that hindered swallowing. Conclusions: Postoperative evaluation of patients undergoing subtotal laryngectomy with radioactive-swallow, allows to identify even minimal amounts of fluid aspirated into the bronchial tree and to plan the moment for swallowing to be started.

La laringectomía subtotal supracricoidea asociada con cricohioidoepiglotopexia es la técnica quirúrgica conservadora más eficiente para preservar las funciones laríngeas de los pacientes con carcinoma localmente avanzado de la laringe. La complicación más temida de esta intervención es la aspiración en el momento de la deglución y la neumonía secundaria; existen diversas formas de evaluar la aspiración y el grado de esta. Presentamos una novedosa forma de identificar incluso pequeñas cantidades de aspiración traqueobronquial. Método: Se incluyeron pacientes sometidos a laringectomía subtotal y cricohioidoepiglotopexia por cáncer laríngeo; todos evaluados con trago radiactivo posoperatorio. Con base en la sintomatología y resultado del gammagramma se decidió prolongar el tiempo de alimentación por sonda. Resultados: Se incluyeron 37 pacientes, cuatro habían recibido radioterapia; la tasa de aspiración fue de 29.7 %; 50 % de los pacientes que habían recibido radioterapia presentó aspiración y 18 % de los pacientes con aspiración requirió prolongación del tiempo de alimentación por sonda nasogástrica; ninguno necesitó laringectomía total por aspiración que no permitiera la deglución. Conclusiones: La evaluación posoperatoria de pacientes sometidos a laringectomía subtotal con trago radiactivo permite identificar líquido aspirado al árbol bronquial, incluso en cantidades mínimas, y planear el momento para iniciar la deglución.