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The present study was carried out to evaluate the possible hepatoprotective activities of the medicinal plant Thespesia populnea in carbon tetrachloride (CCl4)-induced liver injury in rats. The water suspension (500 mg/kg b.wt.) of leaf, flower and stem bark of T. populnea showed varying levels of protective action against CCl4-induced liver damage as evidenced from significant reduction in the activities of serum marker enzymes for liver damage (alanine transaminase, aspartate transaminase, and alkaline phosphatase), and bilirubin levels when compared with CCl4-intoxicated control rats. The stem bark suspension showed maximum hepatoprotection compared with leaf and flower. An ethanol extract of the stem bark was more active than n-hexane and water extracts, showing remarkable protection at a dose of 60 mg/kg b.wt. The hepatoprotective effect of this extract was almost comparable to that of silymarin (100 mg/kg), a reference herbal drug. Thus, the present study indicates that ethanol extract of T. populnea stem bark is promising for further studies leading to hepatoprotective drug development.

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Fleshings, an abundant protein source are disposed in large quantity as a solid tannery wastes. Herein, an approach for complete utilization of pre‐treated fleshing waste has been developed to obtain functional rich activated carbon, which can be used as bio‐adsorbent for the removal of chromium(VI) from aqueous solution. In this study, Functional rich Fleshing Waste Activated Carbon (FWAC) was characterized by Thermogravimetric analysis (TGA), (Brunauer–Emmett–Teller) BET, Fourier Transform Infrared Spectroscopy (FT‐IR) and (Scanning Electron Microscope) SEM analysis. The thermal and FT‐IR studies showed innovative functionalities with superior physico‐chemical properties. The functional rich bio‐adsorbent provided greater opportunity to utilise this material as an adsorbent for trapping toxic metal ions. The maximum adsorption capacity of functional rich bio‐adsorbent was found to be 60.8 mg g−1. Effect of pH, temperature, adsorbent dose and metal ion concentration on adsorption of metal ions were thoroughly investigated also the kinetics and thermodynamic study were carried out. The maximum removal of chromium was obtained at pH 3 with ≥97% for about 0.5 g adsorption dose of 100 mg L−1 initial concentration. The fleshings dealt out as solid tannery wastes, now provides ample solution for ecological crisis of toxic chromium(VI). © 2017 American Institute of Chemical Engineers Environ Prog, 36: 1725–1733, 2017