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Administration of β-sitosterol to nephrotoxicity induced rats showed significant positive changes in biochemical parameters, histopathological and immunohistochemical observations, and up-regulation of Nrf2 gene expression. From this, it was clear that β-sitosterol showed renal protective function.

Vigna mungo L. seed coat is an agro by-product, available in substantial quantity, with no clear evidence to prove its economic importance. In the present study, the phytochemicals, proximate content, minerals and in vitro antioxidant activities of aqueous (AE), ethanol (EE) and 80% ethanolic extract (80% EE) of Vigna mungo L. seed coat were determined. The total carbohydrate, total protein, crude fibre, ash and moisture content of the seed coat were found to be 27.52±2.71%, 10.07±0.92%, 48.67±1.96%, 4.87±0.29% and 11.03±0.49% respectively. The content of total phenolics and flavonoids were significantly higher in 80% EE than other extracts. The mineral composition showed that seed coat was rich in calcium, sodium, potassium, magnesium, iron, copper, zinc and manganese. The higher antioxidant potential was shown by 80% EE in DPPH and SOD assay whereas AE shows more scavenging activity in H2O2 assay. So it can be used as neutraceuticals in food supplements.

Vigna mungo L. seed coat is an agro by-product, available in substantial quantity, with no clear evidence to prove its economic importance. In the present study, the phytochemicals, proximate content, minerals and in vitro antioxidant activities of aqueous (AE), ethanol (EE) and 80% ethanolic extract (80% EE) of Vigna mungo L. seed coat were determined. The total carbohydrate, total protein, crude fibre, ash and moisture content of the seed coat were found to be 27.52±2.71%, 10.07±0.92%, 48.67±1.96%, 4.87±0.29% and 11.03±0.49% respectively. The content of total phenolics and flavonoids were significantly higher in 80% EE than other extracts. The mineral composition showed that seed coat was rich in calcium, sodium, potassium, magnesium, iron, copper, zinc and manganese. The higher antioxidant potential was shown by 80% EE in DPPH and SOD assay whereas AE shows more scavenging activity in H2O2 assay. So it can be used as neutraceuticals in food supplements.