Angioleiomyomas are relatively common neoplasms in skin and superficial planes of extremities (89%), head (48%) and trunk (14%). These tumours are extremely rare in uterus with very few cases described in the literature. These cases have been described with varied names like angiomyoma, angioleiomyoma, or vascular leiomyoma. There is no description of angioleiomyoma as an entity or as a variant of leiomyoma in the latest WHO classification of uterine tumours. There is a mention of vascular leiomyoma as a differential diagnosis of hemangioma under rare mesenchymal tumors but no description provided. A proposal has been made by Glenn Mc Cluggage et.al that angioleiomyoma should be included among the benign leiomyoma variants in the next WHO classification.
Bone is one of the common sites for distant metastasis from breast cancer. About 6%-10% of breast carcinomas have already spread to distant sites at the time of initial diagnosis. Presence of bone metastasis affects patient's prognosis and the planning of treatment. We report a case of 32year old female who presented with a subtrochanteric fracture left femur and multiple osteolytic lesions throughout the axial skeleton leading to clinical suspicion of multiple myeloma. Hematological work up suggested a metastatic deposit. Subsequent detailed examination revealed a breast lump in right breast. On core biopsy it was diagnosed as duct cell carcinoma. This report addresses the role of bone marrow examination in arriving at a diagnosis in multiple osteolytic lesions which pose wide differential diagnoses.
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