Potentiometric titration of chloride with silver nitrate has been a standard procedure for many years, and the theoretical considerations involved have been clearly set forth by Kolthoff & Furman (1931). However, methods based on this principle have been little used in biological work, in spite of theirattractivepossibilities. Lehmann(1939)seems to have been the first to describe a method suitable for clinical work; more recently, Norberg (1949) has 02 01 N-AgNOi (ml.

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The measurement of available lysine in high‐protein animal and vegetable meals for use in compounded animal feedingstuffs, is discussed. A semi‐automatic method, based on the measurement of total lysine and the lysine remaining after treatment of the meals with fluorodinitrobenzene, is compared for fish and groundnut meals with the established methods of Carpenter and of Rao et al.

SummaryRecent changes in the structure of the examination for M.R.C.P. (U.K.) have prompted a review of these together with a historical outline of the examinations which preceded it at the Royal Colleges of Physicians of Edinburgh, Glasgow, and London.Part I of the examination continues to fulfil its role as a screen and a slight change in the marking system appears to have improved its discriminating powers still further. The major change in part II is the substitution of a more objective written test in place of the essay papers.

In an experiment designed to determine whether or not homografts of parathyroid tissue would survive and function in millipore diffusion chambers, Wilson, Zollinger, Mahan and Brooks (1) subjected female mongrel dogs to parathyroidectomy either in two stages or as a single procedure. Twelve animals with transplants survived the acute postoperative period with its attendant severe hypocalcemia, but all required intensive parenteral calcium support for periods ranging from 19 to 78 days. This supportive therapy could eventually be stopped, and 11 of these dogs were perfectly well in all respects for two to five months prior to removal of their transplants. The range of the serum calcium level was 9 to 11 mg per 100 ml in six of them, and 7 to 8 mg per 100 ml in the other five. However, after all of the millipore chambers were removed, there was little or no alteration in their clinical status or their serum calcium levels. The dogs were followed for two and one-half to four months after the chambers were excised, and the only shift in the level of serum calcium that occurred was in one dog, which, with a serum calcium initially in the 7 to 8 mg per 100 ml range, was later able to maintain a consistent value of 9.0 mg per 100 ml.