A caprylate-dependent autoantibody with specificity for the e antigen of red cells
is described. The antibody was completely inactivated by 2-mercaptoethanol and was probably
of the IgM immunoglobulin class. The antibody had no apparent specificity for albumin.
Reactivity of the described antibody may depend upon conformational change of red cell
Rh antigen by caprylate.
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