ObjectivesPoisoning occurring in childhood still continues to be an important public health issue. The aim of the study is to socio-demographically and clinically examine poisoning cases consulted to emergency department.MethodsThe findings of 121 patients between the ages of 1 month and 17 years consulting to the pediatric emergency department with the suspicion of poisoning were examined retrospectively in the study.ResultsThe mean age of the patients was 6.60 ± 5.70 (min-max: 0–17) years and 49.6% of the patients were male and 50.4% were female. The most common causes of poisoning were corrosive chemicals in 35 patients (28.9%), poisonous animals in 24 patient's (19.8%) and prescription medications in 24 patients (19.8%). While 103 (85.1%) of the cases were exposed to the factor accidently, 18 of the cases (14.9%) had attempted suicide. The mean monthly family income levels of accidently poisoned cases were significantly higher than those who attempted suicide (p < 0.001). The father's education level was lower in cases who were poisoned by suicide attempt than in those who were accidently poisoned (p < 0.001).ConclusionPoisoning rates in childhood and varieties of factors differentiate among the regions. The rate of poisoning cases due to poisonous animals was found to be quite high in the region where this study was carried out. In addition, the study showed that poisoning rates due to suicide attempt in children of families with low income level and/or father's education level have increased.
Bu çalışmanın amacı Şanlıurfa ilinde yanık ünitesinde takip edilen pediatrik yaş grubu tüm olguların klinik özelliklerinin tartışılmasıdır. Materyal ve Metod: Ocak 2019 ile Kasım 2019 tarihleri arasında yanık ünitesinde yatırılarak takip edilen pediatrik yaş grubu 274 olgunun klinik verileri geriye dönük olarak incelendi. Bulgular: Yanık ünitesinde takip edilen 274 olgunun %57,7'si erkek iken %42,3'ü kadındı. Olguların ortalama yaşı 40.27±41,56 ay idi. Olguların %83,2'sinde çay, süt, sıcak su gibi sıvılar, %12,8'inde yangın, %2,6'sında elektrik çarpması ve %1,5'unda ise sıcak objeler yanık sebeplerini oluşturmaktaydı. Olguların %27'sine yara pansumanı ve medikal tedavi, %61,7'sine yara pansumanı ve medikal tedaviye ilave olarak debritman işlemi uygulanırken olguların %11,3'ünde deri grefti işlemi uygulanmıştı. Sonuç: Pediatrik yaş grubu yanık olgularının sıklıkla 1-6 yaş arasında olduğu ve erkek çocukların kız çocuklarına göre daha sık yanık etkenine maruz kaldığı görülmektedir. Deri bütünlüğü bozulduğundan dolayı yanık olgularında hem gram-negatif hem de gram-pozitif enfeksiyon etkenlerinin görülebileceği göz önünde bulundurulmalıdır.
Copeptin is a hypothalamic stress hormone that is synthesized in the hypothalamus together with Arginine-vasopressin and circulated from the neurohypophysis in equimolar amounts and can indicate the individual stress level. The aim of this study was to investigate the plasma copeptin level for childhood migraine headache. In this study, total oxidant status (TOS); total antioxidant status (TAS); oxidative stress index (OSI); and copeptin were measured in the plasma samples of 61 migraine patients and 60 matched healthy participants. The median plasma copeptin levels in the patients group and control group were 298.25 and 194.35 pg/mL, respectively. Copeptin levels were significantly higher in migraine patients than in the healthy control group. The specificity and sensitivity of copeptin for 249.5 pg/dL cut off value predicting diagnosis of migraine were 67% and 64%, respectively. In addition, TOS and OSI levels were found to be higher and TAS levels were significantly lower in patients with migraine than healthy controls. Plasma copeptin levels are thought to increase in cases of childhood migraine secondary to increased oxidative stress. In the diagnosis of childhood migraine cases, it can be used together with oxidative stress biomarkers such as TAS, TOS and OSI as a complementary parameter.
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