There is little about the incidence, mortality and risk factors of Esophageal cancer (EC) in the world. Therefore, the purpose of this study was to determine the incidence rate, mortality and EC risk factors in the world. This review study was conducted on published English research by January 2017 with the search in by March 2018 by searching in the databases of PubMed, Scopus, and Science Direct with the keywords "esophagus cancer," "epidemiology," "incidence," "mortality," "risk factor," " world." Based on the findings of this study, the geographical distribution of the EC differs according to subtitles, as AC is more prevalent in developed countries, while SCC is more prevalent in countries in Africa and East Asia. The most important risk factors for EC are the low intake of vegetables and fruits, drinking drinks and hot liquids, reducing the intake of nutritional supplements such as selenium and zinc, smoking, excessive consumption of alcohol, past medical history, obesity and exposure to some environmental factors. According to the findings, it seems that the main cause of EC- is an undesirable lifestyle. Therefore, it is possible to improve the lifestyle and inform the community about EC risk factors and healthy lifestyle education.

Objective: Tobacco smoking is one of the causes of the incidence and mortality of cancer in the world. This study aimed to review the relationship between TS and especially the use of cigarettes with common cancers of various organs of the body. Methods: This study was  conducted  in  English by November 2017 through a search in databases of the PubMed, Scopus and Web of Science. The search strategy included the key words "cancer", "tobacco smoke", "tobacco smoke", and "smoking." Articles that looked at the relationship between each type of cancer and smoking were entered into the study and summarized in Review. Results: Tobacco smoking is associated with an increased risk of lung cancer, Upper aerodigestive tract, esophagus, stomach, bladder, kidneys, colorectal, prostate, and pancreas. However, further studies are needed to confirm the association between Tobacco smoking and liver, cervical, brain, gallbladder, Hodgkin’s disease, non-Hodgkin’s lymphoma and hematologic malignancies. However, Tobacco smoking plays a protective role in the development of thyroid cancers, skin and Kaposi’s sarcoma. Conclusions: Given that almost all of the risk factors for most cancers are Tobacco smoking, increasing the public’s awareness of the harmful effects of smoking, implementing programs and policies to  reduce smoking, can lead to a reduction in smoking and consequently reduce  the  resulting  harmful  consequences.

Objective: The purpose of this review study was to investigate the association between alcohol consumption and common cancers. Methods: This study was conducted in English by February 2019 to include studies reporting alcohol consumption related cancer risks through a search in data bases of the PubMed, Scopus and Web of Science. The search strategy included the keywords: "cancer", " alcohol consumption or Alcohol Drinking or Underage Drinking ". Articles that looked at the relationship between each type of cancer and consumption of alcoholic beverages were entered in to the study and summarized in review.  Results: alcohol consumption is associated with a decreased risk of some types of cancers including: Renal cell carcinoma and Non-Hodgkin lymphoma. Also, alcohol is independent risk factor for oral and pharyngeal, laryngeal, Esophagus, Stomach, Colorectal, Breast and Liver cancer. However, further studies are required to confirm the association between alcohol consumption and Pancreas, Lung, Prostate, Endometrium, Brain tumour and Bladder cancer risks. Conclusions: Given the role of excessive alcohol consumption in the occurrence of various types of cancers, there is a need for a comprehensive plan for alcohol abuse in the community Keywords: cancer, alcohol consumption, Underage Drinking, Alcohol Drinking