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The structure of the title compound, [Ni(C6H15NO3)2](C7H4NO3S)2, consists of a cationic [Ni(TEA)2]2+ and two anionic (SAC)− moieties (TEA is triethano­lamine and SAC is the saccharinate anion). Two TEA ligands coordinate to the NiII ion through four O atoms and two N atoms acting as tridentate ligands (N,O,O′) in a distorted octahedral environment, with the bond distances [d(Ni—O) = 2.078 (2) and 2.082 (2) Å, and d(Ni—N) = 2.108 (2) Å]. SAC anions participate in intermolecular hydrogen bonding with the hydroxyl H atoms of the TEA ligands to form a three‐dimensional network.

Mathematical models of the drug release have been used in the drug delivery (DD) field for more than 50 years by the scientists in the drug development process. These models not only help scientists to learn the dynamics of the drugs release, but also help them to save money and time by helping to design more effective experiments. There is no model in the literature that covers all drug release scenarios. Also, some system-specific models have complex mathematical equations and these models are not suitable for general use. Zero Order Model, First Order Model, Higuchi Model, Peppas Model and Hixon Crowell Model are used in 85% of drug release studies in total. The popularity of these models comes from their simplicity, easy mathematical expressions and implementation. In this review, mathematical derivations of these five models are shown in detail. The points to be considered during the derivation and the problems that may be encountered are carefully explained along with their solutions. In addition, the application of the models to drug release data and the points to be considered were obtained by writing from the scratch without using any ready software while obtaining the fit function. In this way, many problems are better understood, and their solutions are explained. Finally, the obtained fit functions are interpreted.

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The structures of the title triethanolamine (tea) complexes of Cd(II) and Hg(II) saccharinates, bis(triethanolamine)-kappa3O,N,O';kappa4O,N,O',O"-cadmium(II) 1,2-benzisothiazol-3(2H)-onate 1,1-dioxide, [Cd(C6H15NO3)2](C7H4NO3S)2, (I), and bis(triethanolamine)-kappa3O,N,O';kappa4O,N,O',O"-mercury(II) 1,2-benzisothiazol-3(2H)-onate 1,1-dioxide, [Hg(C6H15NO3)2](C7H4NO3S)2, (II), or [M(tea)2](sac)2, where M is Cd(II) or Hg(II) and sac is the saccharinate anion, reveal seven-coordinate metal ions in both complexes. Both complex cations, [M(tea)2]2+, adopt a monocapped trigonal prism geometry in which the two tea ligands exhibit different coordination modes to achieve seven-coordination. One tea ligand acts as a tetradentate ligand using all its donor atoms, while the other behaves as a tridentate O,N,O'-donor ligand, with one of its ethanol groups remaining uncoordinated. The H atoms of the free and coordinated hydroxyl groups of the tea ligands are involved in hydrogen bonding with the amine N atom, and with the carbonyl and sulfonyl O atoms of neighbouring sac ions, forming an infinite three-dimensional network. A weak pi-pi interaction between the phenyl rings of the sac ions also occurs.

Herein the anticancer, antibacterial, and antifungal effects of the five novel dicyanidoaurate(i)-based complexes have been reported.

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