Genomic-based information is an essential key to precise therapy referred to as personalized medicine. Its application in autoimmune disease treatment will bring the required breakthrough in medicine. Autoimmune diseases are the disease conditions where the body’s immune system recognizes and generate an immune response against self-antigens. There exist different approaches of which precision medicine data can be utilized in the clinical management of autoimmune diseases; this includes diagnosis, prognosis, stratification and treatment response prediction. Different markers exist to guide clinical decision while several others are still being identified and proposed. This chapter highlights data and databases in precision medicine of autoimmune diseases and the pathway for data sharing. The precision medicine of selected autoimmune diseases was discussed, and the different biomarkers utilized in the diagnosis, prognosis, stratification and response monitoring of such condition were considered.
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