Precision Medicine of Autoimmune Diseases

Ajayi, Ayodeji Folorunsho; Adebayo, Oluwadunsin; Adebayo, Emmanuel Tayo

doi:10.5772/intechopen.95248

Cited by 1 publication

(1 citation statement)

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“…Genomic data is an important data in precision medicine. Therefore, most thyroid diseases such as autoimmune thyroiditis are known to have high heritability [8,9]. Studies have reported high rate of Graves' disease in monozygotic twins compared to dizygotic twins (in the range of 50-70%, compared with 3-25% respectively).…”

Section: Introductionmentioning

confidence: 99%

Application of Data Science Approaches to Investigate Autoimmune Thyroid Disease in Precision Medicine

Ajayi¹,

Adebayo²,

Adebayo³

et al. 2022

Hypothyroidism - New Aspects of an Old Disease

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In recent times, the application of artificial intelligence in facilitating, capturing, and restructuring Big data has transformed the accuracy of diagnosis and treatment of diseases, a field known as precision medicine. Big data has been established in various domains of medicine for example, artificial intelligence has found its way into immunology termed as immunoinformatics. There is evidence that precision medicine tools have made an effort to accurately detect, profile, and suggest treatment regimens for thyroid dysfunction using Big data such as imaging and genetic sequences. In addition, the accumulation of data on polymorphisms, autoimmune thyroid disease, and genetic data related to environmental factors has occurred over time resulting in drastic development of clinical autoimmune thyroid disease study. This review emphasized how genetic data plays a vital role in diagnosing and treating diseases related to autoimmune thyroid disease like Graves’ disease, subtle subclinical thyroid dysfunctions, Hashimoto’s thyroiditis, and hypothyroid autoimmune thyroiditis. Furthermore, connotation between environmental and endocrine risk factors in the etiology of the disease in genetically susceptible individuals were discussed. Thus, endocrinologists’ potential hurdles in cancer and thyroid nodules field include unreliable biomarkers, lack of distinct therapeutic alternatives due to genetic difference. Precision medicine data may improve their diagnostic and therapeutic capabilities using artificial intelligence.

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Section: Introductionmentioning

confidence: 99%