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It is concluded that an RGD-modified PEG hydrogel containing PTH(1-34) is an effective matrix system to obtain bone regeneration.

Within the limits of this pilot study, no difference was found between the ceramic implant with ZLA(®) surface and a titanium implant in terms of bone tissue integration. Furthermore, the epithelial attachment favoured this ceramic implant over titanium.

The soft tissue dimensions around all implant prototypes were similar and not affected by the implant surface modification.