Pre-exercise LLLT, mainly with 50 J dose, significantly increases performance and improves biochemical markers related to skeletal muscle damage and inflammation.
This study aimed to determine the effectiveness of photobiomodulation therapy (PBMT) and cryotherapy, in isolated and combined forms, as muscle recovery techniques after muscle fatigue-inducing protocol. Forty volunteers were randomly divided into five groups: a placebo group (PG); a PBMT group (PBMT); a cryotherapy group (CG); a cryotherapy-PBMT group (CPG); and a PBMT-cryotherapy group (PCG). All subjects performed four sessions at 24-h intervals, during which they submitted to isometric assessment (MVC) and blood collection in the pre-exercise period, and 5 and 60 min post-exercise, while the muscle fatigue induction protocol occurred after the pre-exercise collections. In the remaining sessions performed 24, 48, and 72 h later, only blood collections and MVCs were performed. A single treatment with PBMT and/or cryotherapy was applied after only 2 min of completing the post-5-min MVC test at the first session. In the intragroup comparison, it was found that exercise led to a significant decrease (p < 0.05) in the production of MVC in all groups. Comparing the results of MVCs between groups, we observed significant increases in the MVC capacity of the PBMT, CPG, and PCG volunteers in comparison with both PG and CG (p < 0.05). We observed a significant decrease in the concentrations of the biochemical markers of oxidative damage (TBARS and PC) in all groups and muscle damage (creatine kinase-CK) in the PBMT, PCG, and CPG compared with the PG (p < 0.01). The clinical impact of these findings is clear because they demonstrate that the use of phototherapy is more effective than the use of cryotherapy for muscle recovery, additionally cryotherapy decreases PBMT efficacy.
OBJETIVO: Avaliar a influência de atividade física na qualidade de vida e sintomas referidos por um grupo de mulheres pós-menopáusicas. METODOLOGIA: estudo caso-controle envolvendo de 197 mulheres na pós- menopausa com idade entre 50-65 anos: 132 sedentárias e 65 praticantes de exercícios físicos aeróbicos de intensidade leve a moderada. A qualidade de vida e a sintomatologia climatérica foram avaliadas pela Menopause Rating Scale (MRS). Na análise estatística, procedeu-se à análise multivariada por regressão linear múltipla. RESULTADOS: O grupo fisicamente apresentou índices de qualidade de vida significativamente melhores em todos os domínios do instrumento MRS: sintomas sômato-vegetativos (p<0,01), sintomas psicológicos (p<0,01) e geniturinários e sexuais (p<0,01); 63,6% do grupo sedentário e 33,4% do fisicamente ativo referiram sintomas de intensidade moderada a severa. A capacidade cardiorrespiratória se mostrou também significativamente maior entre as mulheres fisicamente ativas (26,5±7,0 ml/Kg/min and 20,2±7,8 ml/kg/min, respectivamente). Através da análise multivariada, mostraram-se fatores preditores da qualidade de vida no presente estudo, a confirmação de atividade física regular (p<0,01) e a renda familiar per capita (p<0,01), de modo que as mulheres fisicamente ativas ou com melhor renda tenderam a referir menor sintomatologia climatérica e melhor qualidade de vida. CONCLUSÕES: No presente estudo, a atividade física regular de intensidade leve a moderada e a renda familiar per capita influenciaram positivamente a qualidade de vida e a intensidade da sintomatologia climatérica.
Low-powered pulsed laser/light demonstrated better results than either low-powered continuous laser/light or high-powered continuous laser/light in all outcome measures when compared with placebo. The increase in CK activity using the high-powered continuous laser/light compared with placebo warrants further research to investigate its effect on other factors related to muscle damage.
Currently, treatment of muscle injuries represents a challenge in clinical practice. In acute phase, the most employed therapies are cryotherapy and nonsteroidal anti-inflammatory drugs. In the last years, low-level laser therapy (LLLT) has becoming a promising therapeutic agent; however, its effects are not fully known. The aim of this study was to analyze the effects of sodium diclofenac (topical application), cryotherapy, and LLLT on pro-inflammatory cytokine levels after a controlled model of muscle injury. For such, we performed a single trauma in tibialis anterior muscle of rats. After 1 h, animals were treated with sodium diclofenac (11.6 mg/g of solution), cryotherapy (20 min), or LLLT (904 nm; superpulsed; 700 Hz; 60 mW mean output power; 1.67 W/cm(2); 1, 3, 6 or 9 J; 17, 50, 100 or 150 s). Assessment of interleukin-1β and interleukin-6 (IL-1β and IL-6) and tumor necrosis factor-alpha (TNF-α) levels was performed at 6 h after trauma employing enzyme-linked immunosorbent assay method. LLLT with 1 J dose significantly decreased (p < 0.05) IL-1β, IL-6, and TNF-α levels compared to non-treated injured group as well as diclofenac and cryotherapy groups. On the other hand, treatment with diclofenac and cryotherapy does not decrease pro-inflammatory cytokine levels compared to the non-treated injured group. Therefore, we can conclude that 904 nm LLLT with 1 J dose has better effects than topical application of diclofenac or cryotherapy in acute inflammatory phase after muscle trauma.
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