Background: Mycobacterium tuberculosis (MTB), Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canetti, and Mycobacterium microti are all members of the MTB complex [MTBC], which cause tuberculosis. Mycobacteria other than TB also known as non-tuberculous mycobacteria [NTM]. Aims and Objectives: The purpose of this study was to see how accurate and efficient the MPT64 Ag fast test and Lowenstein–Jensen (LJ) medium with p-Nitrobenzoic acid (PNB) was in differentiating MTB and NTM. Materials and Methods: This Prospective cross-sectional, diagnostic study was conducted in the department of Microbiology,Chalamadaanandarao Medical college, Karimnagar, Telangana. India. The study was conducted from September 2020 to September 2021. The study was preapproved by the Institutional ethical and research committee. Results: PNB inhibits the growth of MTBC, whereas NTM species were resistant. MPT64 is a protein antigen secreted specifically by the members of MTBC. This study was carried out to establish the accuracy and efficiency of LJ medium with PNB and MPT64 immunochromatography test (ICT) in differentiation between MTB and NTM. Of the 426 culture positive isolates tested, 382 (89.67%) were recovered from pulmonary specimens and 44 (10.32) from extrapulmonary sources. Of the 426 isolates tested for the presence of MPT64 antigen, 407 (95.53%) were found positive for ICT test. Whereas, 18 (4.22%) isolate and were considered as NTM and 408 as MTBC (95.77%) by selective inhibition by PNB in LJ medium. Conclusion: According to our findings, the SDbioline kit is a fast, accurate, and reliable approach for separating MTB from NTM for TB management. MPT64ICT results were compared to culture smear results, which was particularly informative in the situation of MPT64ICT negative isolates with liquid cultures.
Chronic kidney disease (CKD) is featured by a progressive decline of kidney function and is mainly caused by chronic diseases such as diabetes mellitus and hypertension. CKD is a complex disease due to cardiovascular complications and high morbidity; however, there is no single treatment to improve kidney function in CKD patients. Since biological markers representing oxidative stress are significantly elevated in CKD patients, oxidative stress is receiving attention as a contributing factor to CKD pathology. Aim of our study is comparison of oxidant and anti oxidant parameters in chronic renal failure, Hemodialysis (pre and post) and control subjects. Materials and Methods: The present study was conducted on a patient group comprising of 50 patients diagnosed with CRF, 50 were pre hemodialysis, 50 were post hemodialysis (MHD). This patient group was compared to a healthy group including 100 controls. All the study participants were admitted in the department of Medicine [Nephrology department] at “Rajiv Gandhi Institute Of Medical Sciences”, Kadapa. Andhra Pradesh. India. Study Period : July 2020 to December 2020 ,The obtained serum samples were used for biochemical analysis for estimating MDA, vitamin A and Glutathione Peroxidase (GPx).
There is an increasing incidence of coronary artery disease in India. We therefore need a tool to evaluate the severity and prognosis of this acute myocardial infarction. In acute myocardial infarction, the function of plaque rupture and inflammation has already been identified. Aim: To study the organization of LDL-C/HDL-C ratio and inflammatory marker CRP in acute myocardial infarction. Methods and Material: Patients who have been diagnosed as acute myocardial infarction (ST Elevation Acute myocardial Infarction or Unstable angina/Non ST Elevation Myocardial Infarction) and admitted to ICCU of Government of medical sciences, Kadapa, AP. July 2021 to December 2021, are the subjects. Sample consists of 100 cases of acute myocardial infarction. Case history was taken from the patients, and studied according to proforma. Conclusion: Elevated levels of CRP are independent indicators of adverse effects. When contrast with the LDL / HDL ratio, CRP is used for risk stratification and as a prognostic predictor. These findings suggest that in patients with acute myocardial infarction, raised CRP Levels is significant as compared to LDL/HDL ratio.
Osteomyelitis is an infection and inflammation of the bone. Bacteria are the primary cause of osteomyelitis. Infections with fungi and viruses can also cause it.It usually affects children and others who are immunocompromised. Although bacteria cannot colonise bone ordinarily, events such as trauma, ischemia, surgery, the presence of foreign particles, or the insertion of prostheses can disrupt bone integration, eventually leading to infection.AIM : To study Bacteriological profile of osteomyelitis patients in Government Hospital, Ambikapur. Material And Material: During the study period of April2021 to Oct 2021 for this study 30 patients who were diagnosed clinically and radiologically as a case of Chronic Osteomyelitis are participating in this study. The risk factors for Chronic Osteomyelitis were obtained from patient case sheets with the help of orthopedic surgeons in the department of orthopedic RSDKSGMC and Hospital.In this study, the total number of cases Chronic Osteomyelitis considered was 30.with age group of 1-60 years and both the sexs. Conclusion: Chronic osteomyelitis is a chronic disease that affects the long bones, particularly the femur and tibia, and is most common in adults. Haematogenous Osteomyelitis is becoming less common as antibiotics become more widely available and children's growing bones have a higher vascular metaphysis.
Any bacterial cells found in the blood should raise concern because it is sterile. Bacteremia is the term used to describe the presence of live, transitory bacteria in the blood. However, in the majority of bacteremic conditions, only a tiny number of bacterial cells enter, and no symptoms appear because the transients are quickly eliminated. immune blood cells eliminate. Aim: a study of blood stream infesctions in intensive care units, government hospital,ambikapur. MATERIALS AND METHODS :The study was carried out in the department of microbiology, central laboratory RSDKSGMC and Hospital, Ambikapur, CG. STUDY PERIOD: Oct 2021 to Dec 2021.Total 150 Number of patients. The study was approved by the ethical committee of RSDKS GMC, Ambikapur, Surguja, C.G. with reference number 2388A/GMC/2021/06-04-2021. CONCLUSION: To enhance the clinical outcome of BSIs in the ICU setting, several techniques should be put into practise. An immediate start to an investigation is still crucial.effective antibiotic therapy that should be personalized. Depending on the source of the illness in each individual patient,the likelihood of antibiotic resistance as well as the most frequently isolated bacteria.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.