Chronic kidney disease (CKD) is featured by a progressive decline of kidney function and is mainly caused by chronic diseases such as diabetes mellitus and hypertension. CKD is a complex disease due to cardiovascular complications and high morbidity; however, there is no single treatment to improve kidney function in CKD patients. Since biological markers representing oxidative stress are significantly elevated in CKD patients, oxidative stress is receiving attention as a contributing factor to CKD pathology. Aim of our study is comparison of oxidant and anti oxidant parameters in chronic renal failure, Hemodialysis (pre and post) and control subjects. Materials and Methods: The present study was conducted on a patient group comprising of 50 patients diagnosed with CRF, 50 were pre hemodialysis, 50 were post hemodialysis (MHD). This patient group was compared to a healthy group including 100 controls. All the study participants were admitted in the department of Medicine [Nephrology department] at “Rajiv Gandhi Institute Of Medical Sciences”, Kadapa. Andhra Pradesh. India. Study Period : July 2020 to December 2020 ,The obtained serum samples were used for biochemical analysis for estimating MDA, vitamin A and Glutathione Peroxidase (GPx).
There is an increasing incidence of coronary artery disease in India. We therefore need a tool to evaluate the severity and prognosis of this acute myocardial infarction. In acute myocardial infarction, the function of plaque rupture and inflammation has already been identified. Aim: To study the organization of LDL-C/HDL-C ratio and inflammatory marker CRP in acute myocardial infarction. Methods and Material: Patients who have been diagnosed as acute myocardial infarction (ST Elevation Acute myocardial Infarction or Unstable angina/Non ST Elevation Myocardial Infarction) and admitted to ICCU of Government of medical sciences, Kadapa, AP. July 2021 to December 2021, are the subjects. Sample consists of 100 cases of acute myocardial infarction. Case history was taken from the patients, and studied according to proforma. Conclusion: Elevated levels of CRP are independent indicators of adverse effects. When contrast with the LDL / HDL ratio, CRP is used for risk stratification and as a prognostic predictor. These findings suggest that in patients with acute myocardial infarction, raised CRP Levels is significant as compared to LDL/HDL ratio.
Between March 2012 and March 2022, 138 paediatric burns patients under the age of one year were hospitalized and managed at Department of Burns and Plastic surgery at Pandit Dindayal Upadhyay Civil Hospital, Rajkot, Gujarat, India. Out of these patients, 61.59% (n=85) were males and 38.40%(n=53) were females. Aetiology of burns was mostly ame burns, scald burns from water and milk and electrical burns. TBSA (total body surface area) percentage sustained from burn trauma ranged from 1% to 95 %. Flame burns and water scald burns contributed to higher percentage of burns as compared to milk scalds and electrical burns. Total mortality was 23.91% (n=33). Flame burns resulted in 16 mortalities and scald burns lead to 14 deaths. These results show that mortality in infant is higher than other paediatric age groups. Infants represent a specic vulnerable group because they are essentially non-walkers and entirely dependent on their parents. More often than not these burns are due to negligence on the part of parents. These burns can be prevented by awareness campaigns targeting education of parents and care givers.
Celebration of various cultural and religious festivals as well as holidays involves use of reworks. Injuries due to reworks is essentially a preventable injury .The aim of this article is to review cases of burns and associated trauma due to reworks at a regional burns and plastic surgery unit in India .A retrospective review was performed in all patients presenting to our centre with burn injuries due to reworks over a period of ten years from March 2012 to March 2022. A Total 463 patients were identied. Cases were studied in terms of patients' demographics, trend of rework injuries throughout the year, mechanism of injuries, anatomical region wise involvement of burn injuries. Conservative and surgical treatment was provided according to the extent of burn injuries. Various treatment given and outcomes of treatment were recorded. Mean duration of hospital stay and recovery time was noted .Most injuries occurred in October and November (around the Diwali festival) Mechanism of injury were mostly ame burns, contact burns and injury from blast force. Most common injuries were sustained to hands, head and neck region and torso.A total of 54 (11.66 %) patients needed surgery. Fireworks can lead to burn injuries, a range of soft tissue injuries, fractures, as well as eye injuries.The severity of rework injuries can effectively by reduced by proper planning which involves preparedness of work force, awareness campaigns and educating public about safety measures.
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