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Background: The role of the pharmaceutical industry in a country such as Nigeria in the provision of safe, high quality and efficacious pharmaceutical products to meet the healthcare need of the populace, cannot be over-emphasized. This study was undertaken to critically look at the issues affecting Medicines’ Security in Nigeria. Methods: A self-completion questionnaire was used for data collection. The questionnaire was administered to participants of an Industry event in September 2017. Data collected were analyzed using Statistical Package for Social Science. Results: A total number of 800 questionnaires were administered to the participants and 529 of the questionnaires were included for analysis. Male participants (58.6%) were more than female participants, all age groups were well represented and more than a third of the respondents had first degree as their minimum qualification. Majority of the respondents (91.3%) indicated that Ministry of Health and its agencies were key to protecting the pharmaceutical sector, while slightly less of that proportion (79.1%) indicated that they patronized Nigeria pharmaceutical products. Almost all the participants (91.7%) supported the need for the local pharmaceutical industry to have access to sustainable funding and other incentives. A similar proportion (89.6%) of the respondents indicated that the local pharmaceutical industry should be prioritized in policy making and implementation. A significant proportion of the study participants (82.3%) indicated that access to medicines in Nigeria is a security issue. Conclusion: To ensure Medicines’ Security and attain medicines self-sufficiency in Nigeria, radical policies must therefore be put in place, together with enabling good business and industrial environment by the government in order to protect, promote and grow the local pharmaceutical industry in Nigeria.

Sickle cell disease is caused by an abnormality of the β-globin gene and is characterised by sickling of the red blood cells. Globally, sub-Saharan African countries share the highest burden of the disease. This study aimed at critically reviewing studies focusing on challenges of sickle cell anaemia in sub-Saharan Africa. A literature search was carried out in five major databases. Articles that met the inclusion criteria were included in the bibliometric review and critical analysis. A majority of the studies were undertaken in the West African region (85.5%), followed by Central Africa (9.1%). Very few studies had been undertaken in East Africa (3.6%), whilst the Southern African region had the fewest studies (1.8%). Distribution in relation to country revealed that three quarters of the studies were carried out in Nigeria (74.5%), followed by the Democratic Republic of the Congo (9.1%). According to healthcare settings, a strong majority of the studies were undertaken in tertiary health care facilities (92.7%). Major themes that emerged from the review include interventions, cost of treatment, and knowledge about sickle cell disease. Public health awareness and promotion as well as improving the quality of sickle cell centers for prompt management of patients with sickle cell disorder was identified as a critical strategy towards reducing the burden of the disease in sub-Saharan Africa. To achieve this, governments in countries located in this region need to adopt a proactive strategy in addressing gaps that have been identified in this study, as well as instituting other relevant measures, such as continuous media engagement and public health interventions relating to genetic counselling. Reforms in other areas that can help reduce the disease burden, include training of practitioners and equipping sickle cell disease treatment centers according to World Health Organization specifications.

Amidst growing concerns for environmental degradation by anthropologic activities and use of non-biodegradable materials for industrial and household purposes, a focus on natural polymeric materials offers the veritable prospects for future survival. Although some synthetic polymers are biodegradable, the process of production that is usually non-green adds to environmental pollution. Natural polymers are naturally occurring organic molecules such as cellulose, starch, glycoproteins and proteins. They are mostly obtained from plant sources, but are also produced in animal and microorganisms. One of the most abundant natural polymers of multidimensional and multifaceted application is starch. Starch is used across wide-range applications spanning engineering, food and beverages, textile, chemical, pharmaceuticals and health, etc. This is because it can readily be modified into products of desired physicochemical characteristics, thus making starch a potential tool for industrial and economic revolution. The global trade balance for starch and derived products is about $1.12 trillion, presenting a huge opportunity for more investment in starch production. Africa’s negative starch trade balance of about $1.27 trillion makes it a potential investment destination for starch production. This chapter discusses the use of starch in various industrial sectors, its potentials for sustainable economic development and as a veritable natural polymer for economic revolution.

Adolescents in Africa have low HIV testing rates. Determining the HIV prevalence among this group is very important because adolescents living with HIV (ALHIV) have worse health outcome than other populations of people living with HIV. This study aimed at determining the prevalence of HIV among children of adolescents age (10-18 years) that come for HIV testing in virology laboratory of National Institute for Pharmaceutical Research and Development, Abuja from January 2013 to December 2018. The result was expressed in percentage and disaggregated by sex. Out of 533 adolescents tested over 6 years, 252 (51.9%) females and 234 (48.1%) were males. A total of 69 (14.1%) of them were tested HIV positive which 42 (8.6%) were females and 27 (5.5%) were males. The result of this study indicates that there is epidemics of HIV among adolescents living in Federal Capital Territory Abuja. It is also evident that females are more vulnerable to HIV infection than the males. There is therefore need for urgent standard and comprehensive procedure for adolescents living with HIV transitioning from paediatric to adult care. This also calls for intensive enlightment on HIV education especially in our basic and post basic schools in Abuja.

Introduction Counterfeit medicines are substandard pharmaceutical products that are produced and sold with the intent to deceptively represent their authenticity, origin, or effectiveness. The risk of the existence of such products in healthcare provision remains a significant threat to public health. Pharmacists represent the most critical stakeholders in the supply, manufacture, purchase, and dispensing of pharmaceutical products, and as such can play critical roles in detecting and reducing the circulation of fake medicines. This study aimed to assess the knowledge and practices of pharmacists in Nigeria in relation to counterfeit medicines as well as the challenges associated with preventing and mitigating this menace in the country. Methods A cross-sectional study was undertaken to administer questionnaires to pharmacists across various sectors of practice in Nigeria. Data were analysed using Statistical Package for Social Sciences. Results A total of 390 valid responses were received. The respondents indicated that online drug commerce (72.68%), inadequate inspection (90.93%), inadequate legislation (88.83%), poor collaboration (89.94%), and poor cross-border enforcement (90.43%) were primary challenges to the mitigation of fake medicines circulation in the country. Whilst pharmacists were knowledgeable about counterfeit drugs, gaps were observed in their practices towards detection of these products, as about one-third (30.7%) of the sample indicated that their current knowledge and skills were inadequate to detect counterfeit medicines. Age, years of practice, and area of practice significantly influenced the abilities of the participants to detect counterfeit medicines. Conclusion Evidence from the study revealed that pharmacists had good knowledge of medicine counterfeiting in Nigeria. However, factors such as poor collaboration among regulatory agencies, inadequate inspection and legislation on the regulation of the pharmaceutical sector and online sales of medicines have contributed to the circulation of counterfeit medicines, and this has in turn affected healthcare services in the country.

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Aim: Asthma is a condition that affects the airways in human lungs. It causes its (lungs) inflammation and hyper-responsiveness. Conventional therapies used in its management are expensive and have been found to come with undesirable side effects. The use of herbal remedies in treating the disease is widespread especially in local communities with little or no access to primary health care. This indigenous knowledge on the cure of asthma is gradually being lost among the populace. This study is aimed at documenting local remedies used in the management of asthma. Methodology: Ethnobotanical survey was carried out in Federal Capital Territory (FCT)- Abuja and surrounding communities, among Traditional Medicine Practitioners (TMPs), Herb’s sellers and elderly in the community using semi-structured questionnaire and interview methods. Data were analysed using descriptive statistics and ethnobotany index. Results: 80 respondents were interviewed, 58 of them laid claims to knowledge about medicinal plants used in asthma management. Majority of the respondents are Traditional  Medicine Practitioners (48%). 59 plants species belonging to 38 plant families was documented with most belonging to the Moraceae plant family (10%). The recipes mentioned were mostly prepared as decoctions which are taken orally with a case of two being by smoking and inhalation.    Conclusion: This study has shown that the Federal Capital Territory and settlements within its environ are blessed with medicinal plants used in the management of asthma which serve as a cheap and alternative source of remedy for the local populace and as well, being a repository for scientific inquest that may lead to yet another drug discovery from plant origin used in the management of asthma.