The antioxidant activity (AA) of various extracts of grape marc (Vitis vinifera L.) was studied. Radical absorption activity (RAA) was calculated in reactions with DPPH+ and ABTS•+ radicals and AA in rat liver homogenate by two markers of oxidative stress (OS): contents of thiobarbiturative products and carbonyl groups of proteins. All the extracts showed antioxidant activity. Water-based extract and 96 % ethanol extract obtained via heat bath method were inhibitors of the formation of free radical oxidation of lipids and proteins. 96% ethanol extract is promising for the development of pharmaceutical and cosmetic products.
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