Our analysis of macro preparations and microscopic observation of histological sections of uterus have shown that in case of chlamydia or mycoplasma infection even clinically healthy animals have observed changes in the tissues of the uterus in the form of degeneration, hyperplasia and fibrosis. The consequence of chronic inflammation of chlamydia and mycoplasma infections is the thickening of affected mucosal tissue, epithelial metaplasia in multi-flat epithelium, followed by growth of connective scar tissue. This leads to future infertility or acute endometritis when joining secondary microflora. In animals with obstetric and gynecological pathology diagnosed with chlamydia and mycoplasma infections are characterized by proliferative, degenerative and necrotic changes in all layers of the uterus, changes in the form of cystic or chronic lymphocytic endometritis. Chlamydia and mycoplasma infections not only cause inflammatory diseases of the genital organs, but are a pathogenetic factor in the tumors of the uterus. Clinically healthy animals without chlamydia and mycoplasma infections doesn't have pathological changes in the uterus.
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