At present, there is no definitive opinion on the effect of thyroid hormones on bone metabolism, as the dualism of their effects has been proven. Various studies show mixed data on metabolic changes in periodontal tissues on the background of thyroid dysfunction. Bone tissue plays a key role in the complex system of mechanisms of regulation of calcium and phosphorus homeostasis in the body. The processes of modeling and remodeling of bone and its mineralization are closely related to calcium metabolism. The biochemical manifestation of osteoporotic processes in the cell bone in generalized periodontitis is a violation of calcium-phosphorus homeostasis on the background of altered markers of bone metabolism. According to the literature, it is known that the main indicator of calcium-phosphorus metabolism is the content of calcium in the serum. However, for the metabolic characteristics of the inflammatory-dystrophic process in the cell bone, it is necessary to study the level of inorganic phosphorus and calculate the molar ratio of calcium / phosphorus. The calcium / phosphorus ratio in the blood is important for the study of calcium deposits in bone tissue. Maintenance of normal bone structure depends on the exchange of phosphates between blood and bone tissue. Magnesium along with calcium is needed to achieve optimal bone mineral density. Magnesium helps maintain normal levels of calcium in bone tissue, its constant renewal in bone, prevents calcium loss. With limited intake of magnesium, the formation of calcium phosphate is inhibited. In order to establish indicators that would reflect the peculiarities of metabolic disorders in the organic matrix of the cell process, which is the main component of the periodontium, we conducted biochemical studies, which included the study of calcium-phosphorus metabolism and serum magnesium in patients with primary hypothyroidism and persons without endocrine pathology. According to the results of studies, in young people with generalized periodontitis on the background of reduced thyroid function, there were violations of calcium-phosphorus metabolism in the serum, which consisted of hypocalcemia and decreased calcium-phosphorus ratio. This may indicate abnormalities in calcium intake and absorption in patients with hypothyroidism. We attribute this fact to the fact that for the normal absorption and metabolism of calcium, thyroid hormones are needed, the production of which is reduced in this endocrine pathology. Data on the negative changes of calcium-phosphorus homeostasis, and especially the violation of calcium absorption by patients with generalized periodontitis in young people with primary hypothyroidism, should be considered when developing schemes for the treatment and prevention of periodontal disease in this category of patients.
One of the main tasks of modern higher education is to train specialists with a high level of competence who can constantly work on themselves. The relevance of the research topic is due to the need for continuous professional development of future dentists and the motivation of their training, and the development of an active life position in modern society. The purpose of our work is to study aspiration peculiarities of IFNMU students and interns to the successful and versatile improvement of personality. The personal qualities of the doctor provide comfortable psychological contact with the patient and maintain professional activities dedication. Communicative competence is the subject of special research in the field of future doctors' training. Professional communication is considered to be one of the components of the general culture of relations and contributes to the successful career of a specialist in any sphere of activity, especially the medical one. The problem of forming and maintaining educational interest to master the future specialty of students and interns continues to exist. Motivational components and factors that affect the professional and personal development of the future doctor increase with each year of study, and this process should not stop for life. It’s effectiveness depends on the forms of the material presentation. The presence or absence of positive motives in students and interns have a significant impact on educational activities. Insufficient motivation cannot contribute to the formation of their high professional realization. Therefore, a genuine and persistent desire to acquire knowledge and skills should be the starting point in the formation of a highly qualified healthcare professional. The main factor influencing the interest in the education of students and interns is the acquisition of knowledge, skills, and abilities, which will form the foundation of professional activity in the future. The following factors contribute to increase the motivation of learning: the method of learning the material, its content, teaching methods; usage of problem tasks at each stage of the class; application of interactive technologies. Our analysis showed that gaining knowledge among students and interns is dominated by professional motives: to become a highly qualified dentist and to find a job that meets personal desires in the occupation of their choice. Thus, learning is more effective when it is motivated, and the activities of students coincide in direction and purpose. As a result, the graduate's professional training becomes successful. The effectiveness of the educational process depends on the variety of forms and methods of presenting scientific and practical material. The directions of increasing motivation are as follows: constant improvement and updating of material, the use of interdisciplinary links to understand the importance and practical necessity of each subject in a higher educational establishment, the use of multimedia presentations during practical and lecture classes, work in simulation centers, implementation in the educational process of situational tasks "patient-doctor and doctor-patient" with further discussion and recognition of the flaws of each participants' work. The usage of the latest information technologies and simulation centers helps not only to memorize a large amount of theoretical material but also to obtain practical and communication skills which are necessary for a modern doctor.
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