Precise identification and localization of tumor is the key to success in Mohs micrographic surgery. In a pilot study, we demonstrated improvement in tumor definition and staining characteristics after formalin fixation of cryostat sections (postfixation) when compared with unfixed specimens. We further investigated the benefits of postfixation with a series of tissue fixatives and with varying fixation times. In all cases, postfixation was found to be beneficial. No improvement was noted by extending the postfixation time beyond 1 minute.
In brief Summer's onset means physicians will see many skin conditions they don't usually see at other times of the year. Heat, humidity, and exposure to outdoor elements combine to make skin vulnerable to sunburn, parasite contact, infection, insect bites, and allergic reactions to noxious plants. Most conditions are easy to diagnose and treat, but others are less common and require greater effort to determine the etiology. Rapid recognition along with prevention tips can help keep patients active.
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