Introduction Epilepsy is a neurological disease that interferes negatively with many areas of the patient’s life. Sexual dysfunction is a frequent comorbidity in epileptic patients. Quality of life is particularly affected in women, who are also culturally stigmatized because of their illness. Objectives To assess the sexual function of women with epilepsy compared to healthy women. Methods This was a case-control study of female patients with generalized epilepsy, carried out at the national institute of neurology in Tunisia in 2018. The controls were the patients’ companions in the department. They were matched by age with the cases. Sexual function was assessed by the female sexual function index (FSFI). Results We included 40 cases and 40 controls.Their averge age was 30.45years. In comparison to the controls,the women with epilepsy had less kids ( p=0.04) and more miscarriages (p=0.032). On the other hand, women with epilepsy presented more sexual dysfunctions (p=0. 03) and had a lower total score on the FSFI (p=0.015) as well as significantly lower scores in the domains “desire” (p=0.009), “orgasm” (p=0.026), “satisfaction” (p=0.001) and pain (p=0.015). Conclusions The findings of this study are consisting with the literature, the women with epilepsy in this survey had impaired sexual function. More attention should be paid to these sexual disorders, previously considered secondary or even neglected. Disclosure No significant relationships.
Introduction Suicide is a dramatic suicidality complication and a significant worldwild public health problem. Sixty percent of suicidal deaths are preceded by at least one suicide attempt. Objectives to search and estimate the factors predicting a suicidal recidivism Methods We conducted a retrospective descriptive survey, achieved in psychiatric departement A of Razi hospital on 60 patients hospitalized during a period of 10 years (from January 2010 to December 2019) and have committed at least a suicide attempt. Data collected from medical folders in order to explore sociodemographic and clinical characteristics of the patients. Results The mean age of the sample was 30 years. A high prevalence of female was objectified. There were a low level of education for 53%, most of patients (55%) were unemployed and came from urban area. Among our patients, 39% attempted suicide for a one time. 61% of patients attempted suicide for several times. The main risk factors related to recidivism of suicidal behavior were unemployment, family history of psychiatric disorders and family instability. Conclusions The analysis of these results justifies preventive actions in order to face the increase of suicidal recidivism by searching for these associated factors. Therefore, a multidisciplinary intervention approach is required. Disclosure No significant relationships.
Introduction Mixed states in mood disorders present significant clinical and prognostic challenges. Although the DSM-5 has broadened diagnostic criteria for mixed states with the development of the ‘mixed features’ specifier and its application to unipolar depressive disorders, some mixed episodes might still be overlooked. Objectives to evaluate the frequency and the factors associated with mixed depression according to the broader Koukopoulos criteria in a sample of patients with a major depressive episode Methods We included 99 consecutive patients presenting for a major depressive episode of bipolar (n=10) or unipolar major depressive (n=89) disorder at our outpatient clinic. Major depression was ascertained using SCID- IV criteria, and mixed features were determined using Koukopoulos’ diagnostic criteria Results Mean age of the sample was 35.5 years [14-58]. Women accounted for 63.6% of patients. Mixed features were found in 19.5% (n=19) of the sample, 80% (n=8) among patients with bipolar disorders (BD) and 12.3% (n=11) among those with major depressive disorder (MDD). Individuals with mixed features had more substance abuse (p=0.005) and more suicide attempts (p=0.01). Individuals receiving antipsychotics had a lower risk of mixed features (p=0.000) while antidepressant treatment did not have any affect. A family history of BD, psychosis, suicide and substance abuse were found in these patients. Mixed features in depression were more frequent in patients with BD than in MDD. Conclusions Our study showed a high frequency of mixed features in depression, especially bipolar depression when Koukopoulos criteria are applied. Special attention should be given to these patients given the association with substance use and suicidality Disclosure No significant relationships.
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