Experimental transmission patterns involved with the establishment of mange in dogs were studied to ascertain the effective means of infestation model for mange experiments in dogs. A total of eighteen (18) dogs were used out of which three (3) were naturally infested with Sarcoptes scabie var canis. Five (5) healthy dogs were co-mingled with the three (3) donor dogs for direct contact transmission. Another five (5) mange free dogs were aggregated in a kennel recently vacated by mange infested dogs for environmental and formite transmission while the last five (5) healthy dogs had scrapings from a proximate area of mange lesion sites transferred into the pinnae of each dog for experimental and indirect contact transmission. Successful mite transmission with associated clinical features of pruritus, alopecia, erythema, papules and crusts was achieved with co-mingling of mange naïve and mange infested dogs. These clinical features also differed (p \ 0.05) from dogs experimentally infested as this method of transmission was largely unsuccessful. Following the success of the direct contact model closely is the environmental and formite transmission model. Here, healthy dogs were housed in recently vacated mange infested kennels. The direct contact model only differed from the environmental model (p \ 0.05) in the expression of erythema and papules in dogs. Although comingling infested and mange naïve dogs guarantees successful direct contact transmission, exposure of healthy dogs to infested facility would also lead to infestation. This study showed that comingling remain an effective means of infestation model for mange experiments in dogs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.