OBJECTIVES: To test whether or not vascularized interpositional periosteal-connective tissue grafts are as successful as free subepithelial connective tissue grafts in augmenting volume defects in the anterior maxilla. MATERIAL AND METHODS: Twenty subjects with Seibert class 1 ridge defects in the anterior maxilla were randomly, equally assigned to augmentation by vascularized interpositional periosteal-connective tissue graft (test) or free subepithelial connective tissue graft (control). Clinical periodontal parameters at teeth adjacent to the gap were recorded, and conventional impressions were taken prior to surgery (baseline = t0 ) and 1 (t1 ), 3 (t3 ) and 6 (t6 ) months after surgery. The casts were optically scanned, digitized and analyzed for ridge contour changes in the augmented area. Data were subjected to nonparametric statistics. RESULTS: The contour changes in labial distance between baseline and follow-up for the control group were (median, range) 1 mm, 0.37-1.45 (t0 -t1 ); 1.18 mm, 0.39-1.40 (t0 -t3 ); and 0.63 mm, 0.28-1.22 (t0 -t6 ) and for test group 1.21 mm, 0.74-2.47 (t0 -t1 ); 1.26 mm, 0.50-1.71 (t0 -t3 ); and 1.18 mm, 0.16-1.75 (t0 -t6 ). Significantly less shrinkage of the graft was observed in the test group after 6 months (P = 0.03). Clinical periodontal parameters at the neighboring teeth were stable over the follow-up period and did not differ between groups. CONCLUSIONS: Augmentation of single tooth gaps with moderate ridge defects in the anterior maxilla was successfully performed using both techniques. However, after 6 months, sites treated by the pediculated graft were superior in maintaining the initially augmented volume and showed less shrinkage of the graft. This could be attributed to better perfusion of the pediculated graft. Abstract:Objectives: To test whether or not vascularized interpositional periosteal-connective tissue grafts are as successful as free subepithelial connective tissue grafts in augmenting volume defects in the anterior maxilla.Material and Methods: 20 subjects with Seibert class 1 ridge defects in the anterior maxilla were randomly, equally assigned to augmentation by vascularized interpositional periostealconnective tissue graft (test) or free subepithelial connective tissue graft (control). Clinical periodontal parameters at teeth adjacent to the gap were recorded and conventional impressions were taken prior to surgery (baseline=t0) and 1 (t1), 3 (t3) and 6 (t6) months after surgery. The casts were optically scanned, digitized and analyzed for ridge contour changes in the augmented area. Data were subjected to non-parametric statistics.Results: The contour changes in labial distance between baseline and follow-up for the control group were (median; range) 1mm; 0.37-1.45 (t0-t1), 1.18mm; 0.39-1.40 (t0-t3) and 0.63mm; 0.28-1.22 (t0-t6) and for test group 1.21mm; 0.74-2.47 (t0-t1), 1.26mm; 0.50-1.71 (t0-t3) and 1.18mm; 0.16-1.75 (t0-t6). Significantly less shrinkage of the graft was observed in the test group after 6 months (p=0.03). Clinical...

Our findings of significantly elevated serum MMP-9, MPO, NE together with decreased TIMP-1 in smoker CP patients than non-smokers support that smoking together with periodontal destruction may expose/predispose to cardiovascular diseases.

PCOS and gingival inflammation appear to act synergistically on the proinflammatory cytokines IL-6 and TNF-α. Thus, PCOS may have an impact on gingival inflammation or vice versa. Additional studies are warranted to clarify the possible relationship between PCOS and periodontal disease.

A case of myiasis gingiva was diagnosed in an investigation designed to evaluate the histopathological features of the adjacent tissues of 100 advanced periodontal lesions. The patient was a 36-year old female and her chief complaint was discomfort and swelling in the area between the upper left central and lateral incisors. The patient's medical history, review of the symptoms, and family history were non-contributory and her oral hygiene was acceptable. The surgeon was not aware of anything unusual during the operation. Although the Parasitology Department was unable to define the entomologic identification of the infesting parasite from histopathological tissue slides, it was agreed that this case of myiasis might be produced by larvae of genus Sarcophaga or Enterobius vermicularis.

The low level of IL-2R in the EOP group may be interpreted as an insufficient responsiveness to the periodontopathogens, which may be ultimately related with the more severe tissue destruction. Though not significant, the reduced expression of mCD14 in EOP group may also be related with the immune system deficiencies in these patients.