Bima red onion is one of the endemic plants in Bima NTB which has the potential as antifungal because it has the ability to inhibit resistant bacteria which onion extracts in general cannot do. This study aims to determine the potential of the ointment from the active fraction of red onion bima (Allium sp) as an inhibitor of secondary infection of pathogenic fungi that cause diabetic wounds. The study was an in vitro and in-vivo experimental laboratory laboratories research which was analytic exploratory to test the antifungal activity of several active fractions of Bima onion (Allium sp) against fungi that cause secondary infections in diabetic wounds. The results showed information on the preparation of active onion bima shallot ointment was effective in healing wound cuts in mice with an average cure of 78% in active fractions of 10% onion and 73% of active onion bima onion active fraction ointment. This is because the formulation of ointment active fractions with a concentration of 10% ointment has more active substances and some substances contained in the form of flavonoids, phenolics, alkaloids, steroids, and triterpenoids.
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