Limited data are available on pregnant women with COVID-19 and their neonates. We aimed to evaluate the epidemiological and clinical characteristics of newborns born to women infected with COVID-19. A multicenter cohort study was conducted among newborns born to mothers with COVID-19 in 34 neonatal intensive care units (NICUs) in Turkey. Pregnant women (
n
= 125) who had a positive RT-PCR test and their newborns were enrolled. Cesarean section, prematurity, and low-birthweight infant rates were 71.2%, 26.4%, and 12.8%, respectively. Eight of 125 mothers (6.4%) were admitted to an intensive care unit for mechanical ventilation, among whom six died (4.8%). Majority of the newborns (86.4%) were followed in isolation rooms in the NICU. Four of 120 newborns (3.3%) had a positive RT-PCR test result. Although samples taken on the first day were negative, one neonate became positive on the second day and the other two on the fifth day. Sample from deep tracheal aspirate was positive on the first day in an intubated case.
Conclusion
: COVID-19 in pregnant women has important impacts on perinatal and neonatal outcomes. Maternal mortality, higher rates of preterm birth and cesarean section, suspected risk of vertical transmission, and low rate of breastfeeding show that family support should be a part of the care in the NICU.
Trial registration
:
ClinicalTrials.gov
identifier: NCT04401540
What is Known:
• The common property of previous reports was the conclusions on maternal outcomes, rather than neonatal outcomes.
• Published data showed similar outcomes between COVID-19 pregnant women and others.
What is New:
• Higher maternal mortality, higher rates of preterm birth and cesarean section, suspected risk of vertical transmission especially in a case with deep tracheal aspiration during the intubation, and the possible role of maternal disease severity on the outcomes are remarkable findings of this study.
• In contrast to recommendation for breastfeeding, parents’ preference to formula and expressed breast milk due to anxiety and lack of information shows that family support should be a part of the care in the NICU.
In low birth weight newborn infants, NLR is significantly associated with sepsis, intraventricular hemorrhage, bronchopulmonary dysplasia, and a high mortality rate. Also, those infants with NLR are more likely to be born to mothers with chorioamnionitis and they face sepsis and intraventricular hemorrhage more often.
T Th he e e ef ff fe ec ct t o of f p pr re en na at ta al l b br re ea as st t--m mi il lk k a an nd d b br re ea as st t--f fe ee ed di in ng g t tr ra ai in ni in ng g g gi iv ve en n t to o e ex xp pe ec ct ta an nt t m mo ot th he er rs s o on n t th he e b be eh ha av vi io ou ur r o of f b br re ea as st t--f fe ee ed di in ng g O Or ri ig gi in na al l A Ar rt ti ic cl le e S Su um mm ma ar ry y Aim: Currently, training given during pregnancy has been shown to affect the beginning, rate and duration of breast-feeding. The present study aims to inform expectant mothers about breast-milk and breast-feeding via a prenatal training program and to emphasize the advantages of the training.
Material and Method:Trainings on breast-milk and breast-feeding were held for pregnant women on two days in a week. Each expectant mother was given prenatal training once. Data were collected via a questionnaire composed of 42 questions about breast-milk and breastfeeding.Results: A total of 190 mothers, 90 in the training group and 100 in the control group were included in the study. The rate of behaviour of not using water, pacifier, bottle and formula/solid food during the first six months was shown to be significantly higher in the training group. A significant difference in the rate of breast-feeding was found in the first six months. Bottle feeding was found to be the cause of breastfeeding for shorter than six months. Conclusions: It is concluded that the rate and duration of feeding only breast-milk could be increased if pregnant women are given training about breast-milk. (Turk Arch Ped 2011; 46: 74-8)
The literature on neonates with SARS-CoV-2 is mainly concerned with perinatal cases, and scanty data are available about environmentally infected neonates. To fill knowledge gaps on the course and prognosis of neonatal cases, we analyzed 1-year data from the Turkish Neonatal Society in this prospective cohort study of neonates with postnatal transmission. Data from 44 neonatal intensive care units (NICUs), of neonates with positive RT-PCR results at days 5-28 of life, were extracted from the online registry system and analyzed. Of 176 cases, most were term infants with normal birth weight. Fever was the most common symptom (64.2%), followed by feeding intolerance (25.6%), and cough (21.6%). The median length of hospitalization was 9 days, with approximately one quarter of infants receiving some type of ventilatory support. Myocarditis (5.7%) was the most common complication during follow-up. Among the clinical findings, cough (odds ratio [
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