<p>Dua buah senyawa organotimah(IV) yaitu berupa senyawa trifeniltimah(IV) 4-nitrobenzoat (<strong>2</strong>) dan difeniltimah(IV) di-4-nitrobenzoat (<strong>4</strong>) telah berhasil disintesis melalui reaksi antara senyawa trifeniltimah(IV) hidroksida (<strong>1</strong>) dan difeniltimah(IV) oksida (<strong>3</strong>) dengan ligan asam 4-nitrobenzoat (HNBA). Senyawa hasil sintesis dikarakterisasi dengan menggunakan spektrofotomer IR, spektrofotomer UV, spektrometer NMR dan <em>microelemental analyzer</em> untuk melihat kemurnian senyawa<em>. </em>Aktivitas biologis senyawa turunan organtotimah(IV) 4-nitrobenzoat telah diuji terhadap bakteri Gram positif <em>Staphylococcus aureus</em> dan Gram negatif <em>Escherichia coli</em>. Hasil uji dengan metode difusi agar menunjukkan senyawa <strong>2</strong> pada konsentrasi 200 ppm (3,87 × 10<sup>-4 </sup>M) memberikan penghambatan yang lebih efektif dibandingkan senyawa <strong>4, </strong>senyawa awal<strong> 1 </strong>dan<strong> 3 </strong>serta ligan HNBA.</p><p><strong>Synthesis, Characterization, and Antibacterial Activity Test of Organotin(IV) 4-nitrobenzoate.</strong> Two organotin(IV) compounds, namely triphenyltin(IV) 4-nitrobenzoate (<strong>2</strong>) and diphenyltin(IV) di-4-nitrobenzoate (<strong>4</strong>) compounds have been successfully synthesized through a reaction between triphenyltin(IV) hydroxide (<strong>1</strong>) and diphenyltin(IV) oxide (<strong>3</strong>) with 4-nitrobenzoic acid (HNBA) The synthesized compounds were characterized using IR, UV, NMR spectrometer, and a microelemental analyzer to check the compound purity. The biological activity of the organotin(IV) 4-nitrobenzoate derivative was tested against Gram-positive bacteria <em>S. aureus</em> and Gram-negative bacteria <em>E. coli</em>. The test results with the agar diffusion method showed that compound <strong>2</strong> at a concentration of 200 ppm (3.87 x 10<sup>-4</sup> M) provide more effective inhibition than compound <strong>4</strong>, the starting materials<strong> 1 </strong>and<strong> 3</strong>, and<strong> </strong>the ligand HNBA.</p>
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