Variations of tissue proportions and fibre dimensions (fibre length, fibre cross sectional area, fibre wall thickness, fibre wall area, percentage of fibre wall area) of 50 Japanese hardwoods are compared. The fibre cross sectional area showed large variations as compared to fibre length. There is no significant correlation between fibre cross sectional area and fibre wall thickness.The multiple regression analysis showed that fibre wall thickness, percentage of fibre wall material and ray volume are the parameters most closely correlated with basic density.
It has been known that the over-expression of alpha-synuclein, the main protein of Lewy bodies in Parkinson's disease (PD), leads to neurodegeneration in PD models. In this study, the changes in protein expression between the transgenic over-expressing human alpha-synuclein wild type (alpha-synWT) and the control Caenorhabditis elegans were elucidated by fluorogenic derivatization-liquid chromatography/tandem mass spectrometry (FD-LC-MS/MS) proteome analysis, which is a highly selective, sensitive, repeatable and quantitative method for protein identification. Because the alpha-synuclein wild-type worms showed moderate levels of dopamine loss without overt behavioral abnormalities, it was suggested that the changes in proteins in the alpha-synWT are related in the sequence of the formation of Lewy bodies. Among more than 400 protein peaks detected, actin and several ribosomal proteins were identified for the first time as negative markers at early PD stages. Actin was suggested to be one of the important targets in the elucidation of the etiology of neuronal diseases such as PD or other synucleinopathies.
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