The available data of the IL-1A polymorphism point to an association of the genotype 2-2 with EARR. As analyses of individual subgroups showed, with the increase in the extent of EARR there was a recognizable correlation with genotype 2-2. The genotype distribution of the IL-1B polymorphism in patients and control cohorts revealed no indication of a predisposition. Despite the low number of cases in the own cohort, the data collected revealed that the allele 1 of the IL-1B polymorphism in patients with sporadic EARR did not contribute to predisposition, in contrast to familial cases. The results are an initial basis for pre-orthodontic genetic EARR risk analyses.
Platform-switched implants showed very limited peri-implant bone-level alterations. The healing-mode neither affected the total amount nor the temporal patterns of ΔIBL. Thus, the results for the tested implants with a non-rigid implant-abutment connection were similar to results reported previously for implants with a rigid implant-abutment connection.
For patients who received functional orthopaedic treatment for skeletal Class II correction with a fixed functional appliance, reduction to a physiological condyle-fossa relationship occurred bilaterally in the region of the joints. Our study suggests that the improved dental occlusion was not achieved at the price of a change to an unphysiological position in the temporomandibular joints.
Orthodontic treatment with a rigid, fixed functional appliance to correct skeletal distoclusion results in the following side effects on the disc-condyle relationship in the TMJ: the treatment does not have adverse effects on initially physiological disc-condyle relationships; in TMJs with initial partial or total anterior disc displacement, improved disc position can be achieved.
Titanium miniscrews with a polished surface, 1.6 mm in diameter and 8-9 mm long, do not provide stationary anchorage in molar distalization with the periodontally/miniscrew-anchored Distal Jet. When subjected for several months to load from forces that act in reciprocity to the force systems occurring during molar distalization, they fail to remain completely stationary in position in the palatal locations in which they were inserted. However, the combined anchorage setup is sufficient, intraorally and regardless of patient compliance, to largely compensate for the mesially-acting forces that occur reciprocal to molar distalization.
Functional jaw orthopedics for correction of skeletal Class II with the rigid fixed FMA leads to side-effects reflected in the disc-condyle relationship in the temporomandibular joints: no adverse effects were observed in joints presenting an initial physiological disc-condyle relationship, whereas the disc position may improve in joints with initial partial or total anterior disc displacement. In comparison with the baseline findings, we observed no post-treatment restriction in the extent of maximum mouth opening, protrusion, and left and right laterotrusion. Maximum active retrusion increased due to the treatment. MR imaging and MSA only partly cover the same aspects of temporomandibular joint diagnostics.
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