We investigated two lignite quarries in northern Greece for orbital and suborbital 2 climate variability. Sections Lava and Vegora are located at the southern and northern 3 boundaries of the Ptolemais Basin, a northwest southeast elongated intramontane basin that 4
A simple, accurate, sensitive, and precise reversed-phase (RP) high-performance liquid chromatographic (HPLC) method with fluorescence detection allowing the sensitive and specific quantitation of the newer fluoroquinolones levofloxacin and moxifloxacin is described. Moxifloxacin is used as the internal standard for the determination of levofloxacin and vice versa. A single-step liquid-liquid extraction from human plasma is sufficient for both quinolones. The method is linear from 0.1 to 15 microg/mL and 0.2 to 7 microg/mL for levofloxacin and moxifloxacin, respectively, covering the clinically relevant plasma concentration range. The limits of quantitation are 0.05 microg/mL (levofloxacin) and 0.2 microg/mL (moxifloxacin). The method is successfully applied to plasma drug level monitoring in a volunteer receiving single therapeutic doses of levofloxacin or moxifloxacin at two different occasions.
The molecular structure of an Eocene fossil resin (Vastan, Cambay basin, Western India) has been investigated with complimentary spectroscopic techniques. The FTIR spectrum shows strong aliphatic CH x (3000-2800 and 1460-1450 cm -1 ) and CH 3 (1377 cm -1 ) absorptions and less intense aromatic C=C (1560-1610 cm -1 ) absorptions. The major products from analytical pyrolysis are cadalene based bicyclic sesquiterpenoids including some bicadinenes and bicadinanes. The polycadinane products confirm the fossil material as an Angiosperm dammar resin, associated with inputs of tropical rain forests supported by past climates.
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