Backgrounds/objectives:Acne is an inflammatory disease of the pilosebaceous unit (PSU). The over-expression of survivin and insulin-like growth factor (IGF)-I in some fibrotic disorders suggests a possible implication in the pathogenesis of acne and or post-acne scar. We aimed to evaluate their potential role in pathogenesis in acne and post-acne scar.Methods:Serum survivin and IGF-I levels were estimated in 30 patients with acne and post-acne scar compared to 30 controls.Results:There was a statistically significant difference in survivin and IGF-I levels between controls and patients (P < 0.05). However, there was no linear correlation between survivin and IGF-I.Conclusions:Survivin and IGF-I could have a possible role in the pathogenesis of active acne and in post-inflammatory acne scar.

Introduction: female sexual dysfunction (FSD) is a complex and poorly understood condition that affects females of all ages. Female sexual dysfunction has been a cyclic rather than a linear process that emphasizes biologic, psychological, social, hormonal, and environmental factors. Female sexual dysfunction is a high prevalent disorder reaching up to 60% of females with reported higher levels in postmenopausal. Aim of the work: was to estimate prevalence of FSD and its related factors in Elfayoum city. Subject and Method: This study was a cross sectional descriptive study conducted in Elfayoum city included 508 married females (above 21 years old) during the period from September 2016 to March 2017. Results: The prevalence of FSD among studied group was 61.2% versus 38.8% had normal sexual function, desire dysfunction was 42.3%, arousal dysfunction was 39.2%, lubrication dysfunction was 25%, orgasm dysfunction was 58.5%, satisfaction dysfunction was 58.1% and pain was 43.3%. There was statistically significant negative correlation between Female Sexual Function Index (FSFI) score and each of female and husband age, duration of marriage, and number of children. Low mean of FSFI score was found among females with irregular menstrual cycle, using contraceptive, not pregnant, mutilated and females who's their husband had erectile or ejaculation disorders. Conclusion and recommendation: High prevalence of FSD among females in Elfayoum governorate. Many factors are found to affect FSD as FGM, each of female and husband age, duration of marriage, and number of children.

Introduction: Telogen effluvium (TE) is an abnormality of hair cycling that result in an abrupt onset of generalized shedding of telogen hairs from the scalp, with or without an entifiable trigger. Ferritin and vitamin D play an important role in hair follicle differentiation.