<p>In person who is unable to produce HBsAg, anti-HBc antibody is a helpful marker of hepatitis B virus (HBV) infection. In the present study, we have tried to find out the incidence of anti-HBc (IgG and IgM) among blood donors HBsAg negative. People came for donating blood voluntarily or for their relatives (n = 1000) was selected on inclusion and exclusion criteria. Purposefully selected and collated samples were first tested by HBsAg ELISA of third generation reagent. HBsAg negative sample was tested with anti-HBc ELISA. Positive found in the first test was retested. Out of 1,000 samples on duplicate test, 117 positives were detected. The incidence of anti-HBc antibody among apparently healthy blood donors was found 11.7%.</p>
Summary:Two cases of the rare blood group "Bombay phenotype" are discussed here. This rare blood group, Bombay (Oh) was first established by Bhende et al in Bombay (Mumbai), in 1952.In the ABO (ABH) blood group system, the 'O' antigen represents the lack of A or B antigens; however it has the most amount of H antigen. If the H gene is absent, which is extremely rare, H substance can not be formed and subsequent A and B antigens can not also be formed. Absence of H gene results in the Bombay phenotype (Oh) 1-6, 7-13 .
The comparative analysis of haemagglutination Inhibitation (HI)-antibody production against three lentogenic Newcastle disease virus vaccines BCRDV (F-strain), Izovac B1 Hitchner ® (B1 strain) and Cevac New L® (LaSota strain) was analyzed in broiler chicks. For this, three groups A, B and C, each consisted of 30 birds were vaccinated with single dosage at day 9 and the other group of 10 birds was maintained as unvaccinated control. Sera samples obtained randomly from 10 birds of each group on the day 17, 20, 28 and 32 and the HI titers estimated. Maternally derived antibody persisted to a maximum level of 17 day and than declined to minimum or none. The results revealed that vaccination of young birds with locally produced BCRDV by the Department of Livestock Service elevated HI antibody at comparable level with that of commercially available vaccine Izovac B1 Hitchner and Cevac New L®. The F value preformed with mean±SD of 17, 20, 28 and 32 days appeared non significant among the HI titers of the birds vaccinated with BCRDV, Izovac B1 Hitchner® (B1 strain) and Cevac New L®. DOI: http://dx.doi.org/10.3329/bjm.v28i1.11808 Bangladesh J Microbiol, Volume 28, Number 1, June 2011, pp 41-43
Background: The Rhesus Blood Group is one of the most important Blood Group like ABO. Exposure of Rhesus Negative individuals to Rhesus Positive Red Cells by Transfusion and/or Pregnancy is most likely to stimulate the production of Rhesus antibodies. These Antibodies may cause Haemolytic Diseases of Newborn (HDN) and Delayed Haemolytic Transfusion Reaction (DHTR.) Rh-antigens, mainly D, C ,E, e and small c are well developed before birth. d is not present or used hypothetically. The frequency of these antigens can be determined by using five different antisera; anti-D,-C, small c, -E and small e. Based on these Phenotype and Gene frequencies in a particular Population, the most probable Rh Genotype can be determined.Methodology: This cross sectional comparative study was carried out with 1,000 randomized samples of both patient and donors in the department of Transfusion Medicine of Bangabandhu Sheikh Mujib Medical University (BSMMU). The eventual objective of the study was to determine the actual Rhesus phenotype-genotype frequency of Bangladeshi Native population. Sample was collected from both donor and patient. For each Test Saline and Anti Human Globulin Test (AHGT) were employed. Result: The most common genotype, we found, CDe/CDe i.e R1R1 (38.60%) which is the most vulnerable genotype to be immunized, the next group in our study was CDe/cde R1r(29.20%) and next category was CDe/Cde i.e. R1R2 (22.20%). Very rare genotype in our study detected was cDE/cde i.e. R2R (1.90%), cDE/cDE i.e. R2R2 (1.50%) CDE/cDE i.e.R1Rz (0.60%), cde/cde i.e. R0R0 (0.60%). Among Rh (D) Negative samples genotypes found is cde/cde i.e. rr (4.50%, and cde/cde i.e.r'r(0.8%) and Cde/cdE i.e. rr" (0.10%). Frequency distribution of genotype among male and female was also determined.Conclusion: The findings may be used in formulating Clinical Transfusion Practice and to fourmule strategies to prevent Rh Sensitization, may thus also be useful in disputed paternity and genetic study in Bangladesh.Anwer Khan Modern Medical College Journal Vol. 7, No. 2: Jul 2016, P 25-28
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